Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation

Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation : Analysis of AF-RISK. / van Mourik, Manouk J.W.; Artola Arita, Vicente; Lyon, Aurore; Lumens, Joost; De With, Ruben R.; van Melle, Joost P.; Schotten, Ulrich; Bekkers, Sebastiaan C.A.M.; Crijns, Harry J.G.M.; Van Gelder, Isabelle C.; Rienstra, Michiel; Linz, Dominik K.

I: International Journal of Cardiology, Bind 360, 2022, s. 29-35.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

van Mourik, MJW, Artola Arita, V, Lyon, A, Lumens, J, De With, RR, van Melle, JP, Schotten, U, Bekkers, SCAM, Crijns, HJGM, Van Gelder, IC, Rienstra, M & Linz, DK 2022, 'Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK', International Journal of Cardiology, bind 360, s. 29-35. https://doi.org/10.1016/j.ijcard.2022.05.044

APA

van Mourik, M. J. W., Artola Arita, V., Lyon, A., Lumens, J., De With, R. R., van Melle, J. P., Schotten, U., Bekkers, S. C. A. M., Crijns, H. J. G. M., Van Gelder, I. C., Rienstra, M., & Linz, D. K. (2022). Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK. International Journal of Cardiology, 360, 29-35. https://doi.org/10.1016/j.ijcard.2022.05.044

Vancouver

van Mourik MJW, Artola Arita V, Lyon A, Lumens J, De With RR, van Melle JP o.a. Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK. International Journal of Cardiology. 2022;360:29-35. https://doi.org/10.1016/j.ijcard.2022.05.044

Author

van Mourik, Manouk J.W. ; Artola Arita, Vicente ; Lyon, Aurore ; Lumens, Joost ; De With, Ruben R. ; van Melle, Joost P. ; Schotten, Ulrich ; Bekkers, Sebastiaan C.A.M. ; Crijns, Harry J.G.M. ; Van Gelder, Isabelle C. ; Rienstra, Michiel ; Linz, Dominik K. / Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation : Analysis of AF-RISK. I: International Journal of Cardiology. 2022 ; Bind 360. s. 29-35.

Bibtex

@article{7fe9c5991dee4123996e4d1290adcb59,

title = "Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation: Analysis of AF-RISK",

abstract = "Background: To identify the association between comorbidities and left atrial (LA) and right atrial (RA) function in patients with paroxysmal atrial fibrillation (AF). Methods: This is a cross-sectional study. Speckle-tracking echocardiography was performed in 344 patients with paroxysmal AF at baseline, and available in 298 patients after 1-year follow-up. The number of comorbidities (hypertension, diabetes mellitus, coronary artery disease, body mass index > 25 kg/m2, age > 65 years, moderate to severe mitral valve regurgitation and kidney dysfunction (estimated glomerular filtration rate < 60 ml/min/1.73 m2)) was determined and the association with atrial strain was tested. Results: Mean age of the patients was 58 (SD 12) years and 137 patients were women (40%). Patients with a higher number of comorbidities had larger LA volumes (p for trend <0.001), and had a decrease in all strain phases from the LA and RA, except for the RA contraction phase (p for trend 0.47). A higher number of comorbidities was associated with LA reservoir and conduit strain decrease independently of LA volume (p < 0.001, p < 0.001 respectively). Patients with 1–2 comorbidities, but not patients with 3 or more comorbidities, showed a further progression of impaired LA and RA function in almost all atrial strain phases at 14 [13–17] months follow-up. Conclusions: In patients with paroxysmal AF, individual and combined comorbidities are related to lower LA and RA strain. In patients with few comorbidities, impairment in atrial function progresses during one year of follow-up. Whether comorbidity management prevents or reverses decrease in atrial function warrants further study.",

keywords = "Atrial fibrillation, Echocardiography, Left atrial function, Right atrial function, Speckle-tracking echocardiography",

author = "{van Mourik}, {Manouk J.W.} and {Artola Arita}, Vicente and Aurore Lyon and Joost Lumens and {De With}, {Ruben R.} and {van Melle}, {Joost P.} and Ulrich Schotten and Bekkers, {Sebastiaan C.A.M.} and Crijns, {Harry J.G.M.} and {Van Gelder}, {Isabelle C.} and Michiel Rienstra and Linz, {Dominik K.}",

note = "Publisher Copyright: {\textcopyright} 2022 The Author(s)",

year = "2022",

doi = "10.1016/j.ijcard.2022.05.044",

language = "English",

volume = "360",

pages = "29--35",

journal = "International Journal of Cardiology",

issn = "0167-5273",

publisher = "Elsevier Ireland Ltd",

}

RIS

TY - JOUR

T1 - Association between comorbidities and left and right atrial dysfunction in patients with paroxysmal atrial fibrillation

T2 - Analysis of AF-RISK

AU - van Mourik, Manouk J.W.

AU - Artola Arita, Vicente

AU - Lyon, Aurore

AU - Lumens, Joost

AU - De With, Ruben R.

AU - van Melle, Joost P.

AU - Schotten, Ulrich

AU - Bekkers, Sebastiaan C.A.M.

AU - Crijns, Harry J.G.M.

AU - Van Gelder, Isabelle C.

AU - Rienstra, Michiel

AU - Linz, Dominik K.

PY - 2022

Y1 - 2022

N2 - Background: To identify the association between comorbidities and left atrial (LA) and right atrial (RA) function in patients with paroxysmal atrial fibrillation (AF). Methods: This is a cross-sectional study. Speckle-tracking echocardiography was performed in 344 patients with paroxysmal AF at baseline, and available in 298 patients after 1-year follow-up. The number of comorbidities (hypertension, diabetes mellitus, coronary artery disease, body mass index > 25 kg/m2, age > 65 years, moderate to severe mitral valve regurgitation and kidney dysfunction (estimated glomerular filtration rate < 60 ml/min/1.73 m2)) was determined and the association with atrial strain was tested. Results: Mean age of the patients was 58 (SD 12) years and 137 patients were women (40%). Patients with a higher number of comorbidities had larger LA volumes (p for trend <0.001), and had a decrease in all strain phases from the LA and RA, except for the RA contraction phase (p for trend 0.47). A higher number of comorbidities was associated with LA reservoir and conduit strain decrease independently of LA volume (p < 0.001, p < 0.001 respectively). Patients with 1–2 comorbidities, but not patients with 3 or more comorbidities, showed a further progression of impaired LA and RA function in almost all atrial strain phases at 14 [13–17] months follow-up. Conclusions: In patients with paroxysmal AF, individual and combined comorbidities are related to lower LA and RA strain. In patients with few comorbidities, impairment in atrial function progresses during one year of follow-up. Whether comorbidity management prevents or reverses decrease in atrial function warrants further study.

AB - Background: To identify the association between comorbidities and left atrial (LA) and right atrial (RA) function in patients with paroxysmal atrial fibrillation (AF). Methods: This is a cross-sectional study. Speckle-tracking echocardiography was performed in 344 patients with paroxysmal AF at baseline, and available in 298 patients after 1-year follow-up. The number of comorbidities (hypertension, diabetes mellitus, coronary artery disease, body mass index > 25 kg/m2, age > 65 years, moderate to severe mitral valve regurgitation and kidney dysfunction (estimated glomerular filtration rate < 60 ml/min/1.73 m2)) was determined and the association with atrial strain was tested. Results: Mean age of the patients was 58 (SD 12) years and 137 patients were women (40%). Patients with a higher number of comorbidities had larger LA volumes (p for trend <0.001), and had a decrease in all strain phases from the LA and RA, except for the RA contraction phase (p for trend 0.47). A higher number of comorbidities was associated with LA reservoir and conduit strain decrease independently of LA volume (p < 0.001, p < 0.001 respectively). Patients with 1–2 comorbidities, but not patients with 3 or more comorbidities, showed a further progression of impaired LA and RA function in almost all atrial strain phases at 14 [13–17] months follow-up. Conclusions: In patients with paroxysmal AF, individual and combined comorbidities are related to lower LA and RA strain. In patients with few comorbidities, impairment in atrial function progresses during one year of follow-up. Whether comorbidity management prevents or reverses decrease in atrial function warrants further study.

KW - Atrial fibrillation

KW - Echocardiography

KW - Left atrial function

KW - Right atrial function

KW - Speckle-tracking echocardiography

UR - http://www.scopus.com/inward/record.url?scp=85131454843&partnerID=8YFLogxK

U2 - 10.1016/j.ijcard.2022.05.044

DO - 10.1016/j.ijcard.2022.05.044

M3 - Journal article

C2 - 35618104

AN - SCOPUS:85131454843

VL - 360

SP - 29

EP - 35

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

ER -

ID: 313883056