Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview
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Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview. / Jensen, Tina Kold; Skakkebæk, Niels Erik; Jørgensen, Niels; Jensen, Martin Blomberg; Juul, Anders.
I: Ugeskrift for Laeger, Bind 173, Nr. 50, 2011, s. 3253-5.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning
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TY - JOUR
T1 - Antioxidanter og mandlig subfertilitet--en gennemgang af et Cochranereview
AU - Jensen, Tina Kold
AU - Skakkebæk, Niels Erik
AU - Jørgensen, Niels
AU - Jensen, Martin Blomberg
AU - Juul, Anders
PY - 2011
Y1 - 2011
N2 - In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.
AB - In a Cochrane review the authors suggest that treatment with antioxidant supplementation in subfertile men may improve the outcome of live birth and pregnancy rate for infertile couples undergoing assisted reproductive technology cycles. We disagree as publication bias cannot be excluded and most studies were designed to investigate the effects of antioxidant treatment on semen quality. In addition, the men were treated with many different combinations and doses of antioxidants and it is not possible to recommend infertile men on type and dose of antioxidant. Future studies should be large, randomized placebo-controlled trials.
M3 - Kommentar/debat
VL - 173
SP - 3253
EP - 3255
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 50
ER -
ID: 40167212