Antibiotic treatment of community-acquired pneumonia: a questionnaire survey in Danish general practice
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Antibiotic treatment of community-acquired pneumonia : a questionnaire survey in Danish general practice. / Eggers-Kaas, Lotti; Bisgaard, Lise; Thomsen, Janus Laust; Jarbøl, Dorte Ejg; Llor, Carl; Christensen, Morten Bondo; Bjerrum, Lars; Siersma, Volkert; Hansen, Malene Plejdrup.
I: Basic & Clinical Pharmacology & Toxicology, Bind 130, Nr. 1, 2022, s. 151-157.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Antibiotic treatment of community-acquired pneumonia
T2 - a questionnaire survey in Danish general practice
AU - Eggers-Kaas, Lotti
AU - Bisgaard, Lise
AU - Thomsen, Janus Laust
AU - Jarbøl, Dorte Ejg
AU - Llor, Carl
AU - Christensen, Morten Bondo
AU - Bjerrum, Lars
AU - Siersma, Volkert
AU - Hansen, Malene Plejdrup
N1 - This article is protected by copyright. All rights reserved.
PY - 2022
Y1 - 2022
N2 - BACKGROUND: Discrepancies exist in Danish guidelines for the treatment of bacterial community-acquired pneumonia (CAP). This study aimed to investigate how GPs treat adults with CAP and explore associations between GP characteristics and treatment duration.METHODS: In autumn 2020, GPs in the North Denmark Region were asked to complete an electronic questionnaire on antibiotic prescribing for CAP. Information about GP gender, age, experience and type of practice was obtained. Multivariable logistic regression was used to analyse the association between GP characteristics and treatment duration.RESULTS: A total of 298 GPs were invited to participate of whom 108 completed the survey. Penicillin V was used as first line treatment for CAP by all participants. Treatment duration varied from five (54.6%) to ten days (8.3%). A 5-day course of penicillin was less likely to be prescribed by male GPs (odds ratio (OR) 0.35, 95% confidence interval (CI) 0.13 to 0.94) and more likely to be prescribed by GPs with 5-9 years of experience in general practice (OR 5.03, 95%CI 1.09 to 23.21) compared to those with 10-19 years of experience.CONCLUSION: Variation in antibiotic treatment of CAP emphasises the importance of generating solid evidence about the optimal duration regarding both effectiveness and safety.
AB - BACKGROUND: Discrepancies exist in Danish guidelines for the treatment of bacterial community-acquired pneumonia (CAP). This study aimed to investigate how GPs treat adults with CAP and explore associations between GP characteristics and treatment duration.METHODS: In autumn 2020, GPs in the North Denmark Region were asked to complete an electronic questionnaire on antibiotic prescribing for CAP. Information about GP gender, age, experience and type of practice was obtained. Multivariable logistic regression was used to analyse the association between GP characteristics and treatment duration.RESULTS: A total of 298 GPs were invited to participate of whom 108 completed the survey. Penicillin V was used as first line treatment for CAP by all participants. Treatment duration varied from five (54.6%) to ten days (8.3%). A 5-day course of penicillin was less likely to be prescribed by male GPs (odds ratio (OR) 0.35, 95% confidence interval (CI) 0.13 to 0.94) and more likely to be prescribed by GPs with 5-9 years of experience in general practice (OR 5.03, 95%CI 1.09 to 23.21) compared to those with 10-19 years of experience.CONCLUSION: Variation in antibiotic treatment of CAP emphasises the importance of generating solid evidence about the optimal duration regarding both effectiveness and safety.
U2 - 10.1111/bcpt.13684
DO - 10.1111/bcpt.13684
M3 - Journal article
C2 - 34747101
VL - 130
SP - 151
EP - 157
JO - Basic and Clinical Pharmacology and Toxicology
JF - Basic and Clinical Pharmacology and Toxicology
SN - 1742-7835
IS - 1
ER -
ID: 288709912