Analyzing skin tumor development in mice by the DMBA/TPA model

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

Standard

Analyzing skin tumor development in mice by the DMBA/TPA model. / Li, Hui; Brakebusch, Cord.

Carcinogen-driven mouse models of oncogenesis. red. / Lorenzo Galluzzi; Aitziber Buqué. Bind 163 Elsevier, 2021. s. 113-121 (Methods in Cell Biology).

Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning

Harvard

Li, H & Brakebusch, C 2021, Analyzing skin tumor development in mice by the DMBA/TPA model. i L Galluzzi & A Buqué (red), Carcinogen-driven mouse models of oncogenesis. bind 163, Elsevier, Methods in Cell Biology, s. 113-121. https://doi.org/10.1016/bs.mcb.2020.08.004

APA

Li, H., & Brakebusch, C. (2021). Analyzing skin tumor development in mice by the DMBA/TPA model. I L. Galluzzi, & A. Buqué (red.), Carcinogen-driven mouse models of oncogenesis (Bind 163, s. 113-121). Elsevier. Methods in Cell Biology https://doi.org/10.1016/bs.mcb.2020.08.004

Vancouver

Li H, Brakebusch C. Analyzing skin tumor development in mice by the DMBA/TPA model. I Galluzzi L, Buqué A, red., Carcinogen-driven mouse models of oncogenesis. Bind 163. Elsevier. 2021. s. 113-121. (Methods in Cell Biology). https://doi.org/10.1016/bs.mcb.2020.08.004

Author

Li, Hui ; Brakebusch, Cord. / Analyzing skin tumor development in mice by the DMBA/TPA model. Carcinogen-driven mouse models of oncogenesis. red. / Lorenzo Galluzzi ; Aitziber Buqué. Bind 163 Elsevier, 2021. s. 113-121 (Methods in Cell Biology).

Bibtex

@inbook{54fb484216d54f30b6c168814b8117ab,

title = "Analyzing skin tumor development in mice by the DMBA/TPA model",

abstract = "Mice are the most important animals to model tumor formation and malignant progression in humans. Chemical induction of skin tumors in mice by treatment with DMBA and TPA is a well-studied tumor induction model that is easy to use and directly applicable to genetically modified mice without any mandatory crossing with mice carrying mutations in oncogenes and tumorsuppressors. This article describes the basic protocol for DMBA/TPA induced skin tumor formation and discusses the advantages and limitations of this model, in particular the translatability of results obtained in this system to human cancer patients.",

author = "Hui Li and Cord Brakebusch",

year = "2021",

doi = "10.1016/bs.mcb.2020.08.004",

language = "English",

volume = "163",

series = "Methods in Cell Biology",

publisher = "Elsevier",

pages = "113--121",

editor = "Lorenzo Galluzzi and Aitziber Buqu{\'e}",

booktitle = "Carcinogen-driven mouse models of oncogenesis",

address = "Netherlands",

}

RIS

TY - CHAP

T1 - Analyzing skin tumor development in mice by the DMBA/TPA model

AU - Li, Hui

AU - Brakebusch, Cord

PY - 2021

Y1 - 2021

N2 - Mice are the most important animals to model tumor formation and malignant progression in humans. Chemical induction of skin tumors in mice by treatment with DMBA and TPA is a well-studied tumor induction model that is easy to use and directly applicable to genetically modified mice without any mandatory crossing with mice carrying mutations in oncogenes and tumorsuppressors. This article describes the basic protocol for DMBA/TPA induced skin tumor formation and discusses the advantages and limitations of this model, in particular the translatability of results obtained in this system to human cancer patients.

AB - Mice are the most important animals to model tumor formation and malignant progression in humans. Chemical induction of skin tumors in mice by treatment with DMBA and TPA is a well-studied tumor induction model that is easy to use and directly applicable to genetically modified mice without any mandatory crossing with mice carrying mutations in oncogenes and tumorsuppressors. This article describes the basic protocol for DMBA/TPA induced skin tumor formation and discusses the advantages and limitations of this model, in particular the translatability of results obtained in this system to human cancer patients.

U2 - 10.1016/bs.mcb.2020.08.004

DO - 10.1016/bs.mcb.2020.08.004

M3 - Book chapter

C2 - 33785160

VL - 163

T3 - Methods in Cell Biology

SP - 113

EP - 121

BT - Carcinogen-driven mouse models of oncogenesis

A2 - Galluzzi, Lorenzo

A2 - Buqué, Aitziber

PB - Elsevier

ER -

ID: 274873491