Analysis of morphogenetic mutants of hydra - I. The Aberrant
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Analysis of morphogenetic mutants of hydra - I. The Aberrant. / Schaller, H. C.; Schmidt, T.; Flick, K.; Grimmelikhuijzen, C. J.P.
I: Wilhelm Roux's Archives of Developmental Biology, Bind 183, Nr. 3, 09.1977, s. 193-206.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Analysis of morphogenetic mutants of hydra - I. The Aberrant
AU - Schaller, H. C.
AU - Schmidt, T.
AU - Flick, K.
AU - Grimmelikhuijzen, C. J.P.
PY - 1977/9
Y1 - 1977/9
N2 - A mutant of Hydra attenuata is analysed, the aberrant, which is distinct from the wild type in having a smaller head with fewer tentacles and only half the number of head-specific cells. The rate of head and foot regeneration and the doubling time are slower in aberrants than in normal hydra. The lower head-forming potential is paralleled by a reduced concentration of head-specific morphogens: compared to the wild type, in the aberrant the concentration of head activator is reduced to 70% in the head and to 50% in the body, the concentration of head inhibitor is reduced to 50% in the head and to 80% in the body. The aberrant is more sensitive (3 times) to added head activator and less sensitive (>5 times) to added head inhibitor than the wild type. The slower rate of foot regeneration is paralleled by a lower content of foot-specific morphogens: compared to the wild type, in the aberrant the foot activator is reduced to 40% and the foot inhibitor to 70%.
AB - A mutant of Hydra attenuata is analysed, the aberrant, which is distinct from the wild type in having a smaller head with fewer tentacles and only half the number of head-specific cells. The rate of head and foot regeneration and the doubling time are slower in aberrants than in normal hydra. The lower head-forming potential is paralleled by a reduced concentration of head-specific morphogens: compared to the wild type, in the aberrant the concentration of head activator is reduced to 70% in the head and to 50% in the body, the concentration of head inhibitor is reduced to 50% in the head and to 80% in the body. The aberrant is more sensitive (3 times) to added head activator and less sensitive (>5 times) to added head inhibitor than the wild type. The slower rate of foot regeneration is paralleled by a lower content of foot-specific morphogens: compared to the wild type, in the aberrant the foot activator is reduced to 40% and the foot inhibitor to 70%.
KW - Head formation
KW - Hydra mutant
KW - Morphogenetic substances
UR - http://www.scopus.com/inward/record.url?scp=0017643326&partnerID=8YFLogxK
U2 - 10.1007/BF00867320
DO - 10.1007/BF00867320
M3 - Journal article
AN - SCOPUS:0017643326
VL - 183
SP - 193
EP - 206
JO - Development Genes and Evolution
JF - Development Genes and Evolution
SN - 0949-944X
IS - 3
ER -
ID: 370741976