An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes. / Haukvik, Unn Kristin; Saetre, Peter; McNeil, Thomas; Bjerkan, Petr S; Andreassen, Ole A; Werge, Thomas; Jönsson, Erik G; Agartz, Ingrid.
I: Progress in Neuro-Psychopharmacology & Biological Psychiatry, Bind 34, Nr. 7, 01.10.2010, s. 1259-65.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - An exploratory model for G x E interaction on hippocampal volume in schizophrenia; obstetric complications and hypoxia-related genes
AU - Haukvik, Unn Kristin
AU - Saetre, Peter
AU - McNeil, Thomas
AU - Bjerkan, Petr S
AU - Andreassen, Ole A
AU - Werge, Thomas
AU - Jönsson, Erik G
AU - Agartz, Ingrid
N1 - Copyright © 2010 Elsevier Inc. All rights reserved.
PY - 2010/10/1
Y1 - 2010/10/1
N2 - Smaller hippocampal volume has repeatedly been reported in schizophrenia patients. Obstetric complications (OCs) and single nucleotide polymorphism (SNP) variation in schizophrenia susceptibility genes have independently been related to hippocampal volume. We investigated putative independent and interaction effects of severe hypoxia-related OCs and variation in four hypoxia-regulated schizophrenia susceptibility genes (BDNF, DTNBP1, GRM3 and NRG1) on hippocampal volume in schizophrenia patients and healthy controls.
AB - Smaller hippocampal volume has repeatedly been reported in schizophrenia patients. Obstetric complications (OCs) and single nucleotide polymorphism (SNP) variation in schizophrenia susceptibility genes have independently been related to hippocampal volume. We investigated putative independent and interaction effects of severe hypoxia-related OCs and variation in four hypoxia-regulated schizophrenia susceptibility genes (BDNF, DTNBP1, GRM3 and NRG1) on hippocampal volume in schizophrenia patients and healthy controls.
U2 - 10.1016/j.pnpbp.2010.07.001
DO - 10.1016/j.pnpbp.2010.07.001
M3 - Journal article
C2 - 20638435
VL - 34
SP - 1259
EP - 1265
JO - Progress in Neuro-Psychopharmacology & Biological Psychiatry
JF - Progress in Neuro-Psychopharmacology & Biological Psychiatry
SN - 0278-5846
IS - 7
ER -
ID: 34193844