Age-specific effects of ozone on pneumonia in Korean children and adolescents: A nationwide time-series study
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Age-specific effects of ozone on pneumonia in Korean children and adolescents : A nationwide time-series study. / Kim, Kyoung-Nam; Lim, Youn-Hee; Bae, Sanghyuk; Song, In Gyu; Kim, Soontae; Hong, Yun-Chul.
I: Epidemiology and health, Bind 44, e2022002, 2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Age-specific effects of ozone on pneumonia in Korean children and adolescents
T2 - A nationwide time-series study
AU - Kim, Kyoung-Nam
AU - Lim, Youn-Hee
AU - Bae, Sanghyuk
AU - Song, In Gyu
AU - Kim, Soontae
AU - Hong, Yun-Chul
PY - 2022
Y1 - 2022
N2 - Objectives: To estimate the age-specific effects of 8-hour maximum ozone levels on pneumonia in children and adolescents.Methods: We performed quasi-Poisson regression analyses at 0-4, 5-9, 10-14, and 15-19 years of age using nationwide time-series data from the Republic of Korea (2011-2015). We constructed distributed lag linear models employing a generalized difference-in-differences method and controlling for other air pollutants.Results: A 10.0-ppb increase in 8-hour maximum ozone levels was associated with a higher risk of hospital admissions due to pneumonia at 0-4 (relative risk [RR] = 1.02, 95% confidence interval [CI]: 1.01, 1.03) and 5-9 years of age (RR = 1.06, 95% CI: 1.04, 1.08) but not at 10-14 (RR = 1.01, 95% CI: 0.98, 1.04) or 15-19 years of age (RR = 1.01, 95% CI: 0.97, 1.06). The association between ozone and hospital admissions due to pneumonia was stronger was stronger in cool seasons (from November to April) than in warm seasons (from May to October) but was similar between boys and girls.Conclusion: Short-term exposure to ozone was associated with a higher risk of pneumonia at 0-4 and 5-9 years of age but not at 10-14 or 15-19 years of age. Our findings can help identify vulnerable periods, determine the target populations for public health interventions, and establish air pollution standards.
AB - Objectives: To estimate the age-specific effects of 8-hour maximum ozone levels on pneumonia in children and adolescents.Methods: We performed quasi-Poisson regression analyses at 0-4, 5-9, 10-14, and 15-19 years of age using nationwide time-series data from the Republic of Korea (2011-2015). We constructed distributed lag linear models employing a generalized difference-in-differences method and controlling for other air pollutants.Results: A 10.0-ppb increase in 8-hour maximum ozone levels was associated with a higher risk of hospital admissions due to pneumonia at 0-4 (relative risk [RR] = 1.02, 95% confidence interval [CI]: 1.01, 1.03) and 5-9 years of age (RR = 1.06, 95% CI: 1.04, 1.08) but not at 10-14 (RR = 1.01, 95% CI: 0.98, 1.04) or 15-19 years of age (RR = 1.01, 95% CI: 0.97, 1.06). The association between ozone and hospital admissions due to pneumonia was stronger was stronger in cool seasons (from November to April) than in warm seasons (from May to October) but was similar between boys and girls.Conclusion: Short-term exposure to ozone was associated with a higher risk of pneumonia at 0-4 and 5-9 years of age but not at 10-14 or 15-19 years of age. Our findings can help identify vulnerable periods, determine the target populations for public health interventions, and establish air pollution standards.
U2 - 10.4178/epih.e2022002
DO - 10.4178/epih.e2022002
M3 - Journal article
C2 - 34990535
VL - 44
JO - Epidemiology and health
JF - Epidemiology and health
SN - 2092-7193
M1 - e2022002
ER -
ID: 290060890