A New Technology for Detecting Cerebral Blood Flow: A Comparative Study of Ultrasound Tagged NIRS and (133)Xe-SPECT
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A New Technology for Detecting Cerebral Blood Flow : A Comparative Study of Ultrasound Tagged NIRS and (133)Xe-SPECT. / Schytz, Henrik W; Guo, Song; Jensen, Lars T; Kamar, Moshe; Nini, Asaph; Gress, Daryl R; Ashina, Messoud.
I: Neurocritical Care, Bind 17, Nr. 1, 2012, s. 139-45.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - A New Technology for Detecting Cerebral Blood Flow
T2 - A Comparative Study of Ultrasound Tagged NIRS and (133)Xe-SPECT
AU - Schytz, Henrik W
AU - Guo, Song
AU - Jensen, Lars T
AU - Kamar, Moshe
AU - Nini, Asaph
AU - Gress, Daryl R
AU - Ashina, Messoud
PY - 2012
Y1 - 2012
N2 - There is a need for real-time non-invasive, continuous monitoring of cerebral blood flow (CBF) during surgery, in intensive care units and clinical research. We investigated a new non-invasive hybrid technology employing ultrasound tagged near infrared spectroscopy (UT-NIRS) that may estimate changes in CBF using a cerebral blood flow index (CFI). Changes over time for UT-NIRS CFI and (133)Xenon single photon emission computer tomography ((133)Xe-SPECT) CBF data were assessed in 10 healthy volunteers after an intravenous bolus of acetazolamide. UT-NIRS CFI was measured continuously and SPECT CBF was measured at baseline, 15 and 60 min after acetazolamide. We found significant changes over time in CFI by UT-NIRS and CBF by SPECT after acetazolamide (P ≤ 0.001). Post hoc tests showed a significant increase in CFI (P = 0.011) and SPECT CBF (P
AB - There is a need for real-time non-invasive, continuous monitoring of cerebral blood flow (CBF) during surgery, in intensive care units and clinical research. We investigated a new non-invasive hybrid technology employing ultrasound tagged near infrared spectroscopy (UT-NIRS) that may estimate changes in CBF using a cerebral blood flow index (CFI). Changes over time for UT-NIRS CFI and (133)Xenon single photon emission computer tomography ((133)Xe-SPECT) CBF data were assessed in 10 healthy volunteers after an intravenous bolus of acetazolamide. UT-NIRS CFI was measured continuously and SPECT CBF was measured at baseline, 15 and 60 min after acetazolamide. We found significant changes over time in CFI by UT-NIRS and CBF by SPECT after acetazolamide (P ≤ 0.001). Post hoc tests showed a significant increase in CFI (P = 0.011) and SPECT CBF (P
U2 - 10.1007/s12028-012-9720-2
DO - 10.1007/s12028-012-9720-2
M3 - Journal article
VL - 17
SP - 139
EP - 145
JO - Neurocritical Care
JF - Neurocritical Care
SN - 1541-6933
IS - 1
ER -
ID: 48419721