Bibliografisk note

Funding Information:
The authors thank the UCLA BTTR and Dr. William Yong, UNGC, JCCC Flow Cytometry Core, UCLA Broad Stem Cell Research Center, Dr. Xinmin Li, and the UCLA Clinical Microarray Core for technical contributions. We thank Dr. Robert Damoiseaux and the UCLA Molecular Screening Shared Resource for assistance with shRNA screening. We thank Holly Wilhalme in the UCLA Institute for Digital Research and Education (IDRE) for aid in figure presentation. The IBSP knockout mice were generously supplied by Drs. Martha Somerman and Harvey Goldberg at the National Institute of Arthritis and Musculoskeletal and Skin Diseases. The murine glioma line was a kind gift from Drs. Maria Castro and Pedro Lowenstein. This work was supported by grants from the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (to S.A.G. S.T.C. and H.I.K.), The National Institutes of Health grants P50 CA211015 (to L.L. and H.I.K.), CA241927-01A1 (to S.K.S. and H.I.K.) and CA197943 (to M.L.I-A.), and RO1 NS121617 (to H.I.K.) and RO1 NS112256 (to S.T.C.). This work was also supported by a University of California Cancer Research Coordinating Committee Award, a Broad Stem Cell Research Center Seed Grant, and an American Brain Tumor Association Discovery Award (to S.K.S.). Y.G. S.D.M. A.S. M.C.C. and S.B. performed the experiments and collected and analyzed the data. N.R. performed the cytogenetic experiments. J.M. and D.R.L. contributed to methods and reagents and analyzed the data. L.M.L. and G.W.M. provided clinical samples. F.G. Y.Q. and R.K. performed the bioinformatics analysis. M.L.I.-A. I.N. G.C. S.A.G. S.T.C. S.K.S. and H.I.K. conceptualized and supervised the study. Y.G. S.D.M. A.S. and H.I.K. wrote, edited, and revised the manuscript. S.T.C. is member of the Scientific Advisory Board of Athersys, Fibrobiologics, and San Bio. His laboratory received research support from BrainQ and Universal Cells. S.A.G. is a part-time employee, officer, and stock-holder of Sana Biotechnology, a cell therapy company, and his lab receives sponsored research support from Sana. He is also a co-founder and advisor to CNS2, another cell therapy company from which his lab receives support and in which he holds equity. None of the work described in this paper overlaps with their work with these companies. One or more of the authors of this paper self-identifies as an underrepresented ethnic minority in their field of research or within their geographical location. One or more of the authors of this paper self-identifies as a gender minority in their field of research.

Funding Information:
The authors thank the UCLA BTTR and Dr. William Yong, UNGC, JCCC Flow Cytometry Core, UCLA Broad Stem Cell Research Center, Dr. Xinmin Li, and the UCLA Clinical Microarray Core for technical contributions. We thank Dr. Robert Damoiseaux and the UCLA Molecular Screening Shared Resource for assistance with shRNA screening. We thank Holly Wilhalme in the UCLA Institute for Digital Research and Education (IDRE) for aid in figure presentation. The IBSP knockout mice were generously supplied by Drs. Martha Somerman and Harvey Goldberg at the National Institute of Arthritis and Musculoskeletal and Skin Diseases. The murine glioma line was a kind gift from Drs. Maria Castro and Pedro Lowenstein. This work was supported by grants from the Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (to S.A.G., S.T.C., and H.I.K.), The National Institutes of Health grants P50 CA211015 (to L.L. and H.I.K.), CA241927-01A1 (to S.K.S. and H.I.K.) and CA197943 (to M.L.I-A.), and RO1 NS121617 (to H.I.K.) and RO1 NS112256 (to S.T.C.). This work was also supported by a University of California Cancer Research Coordinating Committee Award, a Broad Stem Cell Research Center Seed Grant, and an American Brain Tumor Association Discovery Award (to S.K.S.).

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