Sergey Vakhrushev
Associate Professor
Glycomics Program
Blegdamsvej 3
2200 København N.
- 2018
- Published
Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts
de Las Rivas, M., Coelho, H., Diniz, A., Lira-Navarrete, E., Compañón, I., Jiménez-Barbero, J., Schjoldager, Katrine Ter-Borch Gram, Bennett, Eric Paul, Vakhrushev, Sergey, Clausen, Henrik, Corzana, F., Marcelo, F. & Hurtado-Guerrero, R., 2018, In: Chemistry: A European Journal. 24, 33, p. 8382-8392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation
King, S. L., Goth, C. K., Eckhard, U., Joshi, Hiren Jitendra, Haue, Amalie Dahl, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Overall, C. M. & Wandall, Hans H., 2018, In: The Journal of Biological Chemistry. 293, 20, p. 7629-7644 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Mapping sites and molecular functions of O-glycosylation
Schjoldager, Katrine Ter-Borch Gram, Wang, S., Joshi, Hiren Jitendra, Mao, Y. & Vakhrushev, Sergey, Dec 2017, In: Glycobiology. 27, 12, p. 1189-1189 47.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Chromogranin A in the mammalian heart: Expression without secretion
Hansen, L. H., Darkner, S., Svendsen, Jesper Hastrup, Henningsen, K., Pehrson, S., Chen, X., Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , Jul 2017, In: Biomarkers in Medicine. 11, 7, p. 541-545 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells
King-Smith, S. L., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Madsen, Thomas Daugbjerg, Dziegiel, Morten Hanefeld, Woetmann, Anders , Vakhrushev, Sergey & Wandall, Hans H., 2017, In: Blood advances. 1, 7, p. 429-442 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins
Larsen, I. S. B., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Siukstaite, L., Harrison, O. J., Brasch, J., Goodman, K. M., Hansen, Lars, Shapiro, L., Honig, B., Vakhrushev, Sergey, Clausen, Henrik & Halim, Adnan, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, p. 11163-11168 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isoform-specific mucin type O-glycosylation maintain epithelial homeostasis
Bagdonaite, Ieva , E.M.H., P., K., L., Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Bennett, Eric Paul, Dabelsteen, Sally & Wandall, Hans H., 2017, In: Glycoconjugate Journal. 34, Suppl. 1, p. S42 1 p., Abstract 78.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Mammalian O-mannosylation of Cadherins and Plexins is Independent of Protein O-mannosyltransferase 1 and 2
Larsen, I. S. B., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Yang, Zhang, Harrison, O. J., Brasch, J., Shapiro, L., Honig, B., Vakhrushev, Sergey, Clausen, Henrik & Halim, Adnan, 2017, In: The Journal of Biological Chemistry. 292, p. 11586-11598Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Global Mapping of O-Glycosylation of Human Herpesviruses
Bagdonaite, Ieva , Norden, R., Joshi, Hiren Jitendra, King-Smith, S. L., Vakhrushev, Sergey, Olofsson, S. & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1408-1408Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Regulation of protein O-glycosylation in epithelial cells - the polypeptide GalNAc-transferases direct cellular differentiation and maintenance of tissue homeostasis
Pallesen, E. M., Bagdonaite, Ieva , Vakhrushev, Sergey, Hansen, Lars, Joshi, Hiren Jitendra, Dabelsteen, Sally & Wandall, Hans H., Dec 2016, In: Glycobiology. 26, 12, p. 1391-1391Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 21237349
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
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135
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A conserved major facilitator superfamily member orchestrates a subset of O-glycosylation to aid macrophage tissue invasion
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119
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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
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