Jens Bukh

Jens Bukh

Professor

Member of:


    1. 2016
    2. Published

      Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir

      Ramirez Almeida, Santseharay, Mikkelsen, L. S., Gottwein, Judith Margarete & Bukh, Jens, Nov 2016, In: Gastroenterology. 151, 5, p. 973-985.e2

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Neutralizing antibodies in patients with chronic hepatitis C and correlation to liver cirrhosis and estimated duration of infection

      Pedersen, J., Lundbo, L. F., Krarup, H., Bukh, Jens & Weis, Nina, Oct 2016, In: Journal of Medical Virology. 88, 10, p. 1791-1803 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      The history of hepatitis C virus (HCV): Basic research reveals unique features in phylogeny, evolution and the viral life cycle with new perspectives for epidemic control

      Bukh, Jens, Oct 2016, In: Journal of Hepatology. 65, 1 Suppl., p. S2-S21

      Research output: Contribution to journalReviewResearchpeer-review

    5. Published

      Functional analysis of microRNA-122 binding sequences of hepatitis C virus and identification of variants with high resistance against specific antagomir

      Li, Y., Pham, Long, Uzcategui, N. & Bukh, Jens, Jun 2016, In: Journal of General Virology. 97, p. 1381-1394

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Hepatitis C Virus Genotype 1 to 6 Protease Inhibitor Escape Variants: In Vitro Selection, Fitness, and Resistance Patterns in the Context of the Infectious Viral Life Cycle.

      Serre, S., Jensen, S., Ghanem, L., Humes, D., Ramirez, S., Li, Y., Krarup, H., Bukh, Jens & Gottwein, Judith Margarete, Jun 2016, In: Antimicrobial Agents and Chemotherapy. 60, 6, p. 3563-3578 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. 2015
    8. Published

      Substitutions at NS3 Residue 155, 156, or 168 of Hepatitis C Virus Genotypes 2 to 6 Induce Complex Patterns of Protease Inhibitor Resistance

      Jensen, S. B., Serre, S. B. N., Humes, D. G., Ramirez Almeida, Santseharay, Li, Y., Bukh, Jens & Gottwein, Judith Margarete, Dec 2015, In: Antimicrobial Agents and Chemotherapy. 59, 12, p. 7426-7436 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge

      Bukh, Jens, Engle, R. E., Faulk, K., Wang, R. Y., Farci, P., Alter, H. J. & Purcell, R. H., Sep 2015, In: Journal of Virology. 89, 17, p. 9128-9132 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Adaptive Mutations Enhance Assembly and Cell-to-Cell Transmission of a High-Titer Hepatitis C Virus Genotype 5a Core-NS2 JFH1-Based Recombinant

      Mathiesen, C. K., Prentø, Jannick, Meredith, L. W., Jensen, T. B., Krarup, H., McKeating, J. A., Gottwein, Judith Margarete & Bukh, Jens, Aug 2015, In: Journal of Virology. 89, 15, p. 7758-7775 18 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Cell culture system of a hepatitis C genotype 3a and 2a chimera: Patent #: 8,945,584

      Gottwein, Judith Margarete, Scheel, T. K. H., Eugen-Olsen, J. & Bukh, Jens, 3 Feb 2015, IPC No. A61K 39/29 (20060101); C12N 15/06 (20060101); C12Q 1/02 (20060101); C07H 21/00 (20060101); C12N 7/02 (20060101); A61K 39/12 (20060101), Patent No. WO2008/125117, 23 Oct 2008, Priority date 11 Apr 2008, Priority No. PCT/DK2008/050083

      Research output: Patent

    12. Published

      Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof: Patent #: 8,946,398

      Gottwein, Judith Margarete, Scheel, T. K. H., Purcell, R. E. & Bukh, Jens, 3 Feb 2015, IPC No. C07H 21/04 (20060101); C07H 21/02 (20060101), Patent No. WO2011/038737, 26 Jul 2012, Priority date 16 Sep 2010, Priority No. PCT/DK2010/050236

      Research output: Patent

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