Mads Lerdrup
Associate Professor
Molecular Aging Program
Blegdamsvej 3
2200 København N.
- 2024
- Published
Single-cell m6A mapping in vivo using picoMeRIP–seq
Li, Y., Wang, Y., Vera-Rodriguez, M., Lindeman, L. C., Skuggen, L. E., Rasmussen, E. M. K., Jermstad, I., Khan, S., Fosslie, M., Skuland, T., Indahl, M., Khodeer, S., Klemsdal, E. K., Jin, K. X., Dalen, K. T., Fedorcsak, P., Greggains, G. D., Lerdrup, M., Klungland, A., Au, K. F. & 1 others, , 2024, In: Nature Biotechnology. 42, p. 591-596 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrator facilitates RNAPII removal to prevent transcription-replication collisions and genome instability
Bhowmick, Rahul, Mehta, K. P. M., Lerdrup, Mads & Cortez, D., 2023, In: Molecular Cell. 83, 13, p. 2357-2366.e8Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival
Lier, S., Rein, K. A., Lund, S., Lång, A., Lång, E., Meyer, N., Dutta, A., Anand, S., Nesse, G., Johansen, R., Klungland, A., Rinholm, J., Boe, S., Anand, A., Pollard, S., Lerdrup, Mads & Pandey, D., 2022, In: Neuro-Oncology. 24, S2, p. ii51 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals
Sankar, A., Mohammad, F., Sundaramurthy, Arun Kumar, Wang, H., Lerdrup, Mads, Tatar, Tülin & Helin, K., 2022, In: Nature Genetics. 54, p. 754–760Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD+ pathway
Maynard, S., Hall, A., Galanos, P., Rizza, S., Yamamoto, T., Gram, H. H., Munk, S. H. N., Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm, Lerdrup, Mads, Maya-Mendoza, A. & Bartek, J., 2022, In: Nucleic Acids Research. 50, 17, p. 9948-9965 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RAD51 protects human cells from transcription-replication conflicts
Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition
Zonderland, Gijs, Vanzo, R., Gadi, Sampath Amitash, Martín-Doncel, E., Coscia, F., Mund, Andreas, Lerdrup, Mads, Benada, Jan, Boos, D. & Toledo, L., 2022, In: Molecular Cell. 82, 18, p. 3350-3365.e7 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Folate Deficiency Triggers the Abnormal Segregation of a Region With Large Cluster of CG-Rich Trinucleotide Repeats on Human Chromosome 2
Garribba, L., Vogel, Ivan, Lerdrup, Mads, Gonçalves Dinis, M. M., Ren, L. & Liu, Ying, 2021, In: Frontiers in Genetics. 12, 695124.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone H4 lysine 20 mono-methylation directly facilitates chromatin openness and promotes transcription of housekeeping genes
Shoaib, Muhammad, Chen, Q., Shi, X., Nair, Nidhi, Prasanna, C., Yang, R., Walter, D., Frederiksen, K. S., Einarsson, H., Svensson, J. P., Liu, C. F., Ekwall, K., Lerdrup, Mads, Nordenskiöld, L. & Sørensen, Claus Storgaard, 2021, In: Nature Communications. 12, 1, 16 p., 4800.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3854
Most downloads
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249
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Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
150
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PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
42
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An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate
Research output: Contribution to journal › Journal article › Research › peer-review
Published