Lars Ellgaard
Professor
Biomolecular Sciences
Ole Maaløes Vej 5
2200 København N.
- 2023
- Published
A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3
Hackney, Celeste Menuet, Flórez Salcedo, P., Mueller, E., Koch, Thomas Lund, Kjelgaard, L. D., Watkins, M., Zachariassen, L., Tuelund, P. S., McArthur, J. R., Adams, D. J., Kristensen, Anders Skov, Olivera, B., Finol-Urdaneta, R. K., Safavi-Hemami, H., Morth, J. P. & Ellgaard, Lars, 2023, In: PLOS Biology. 21, 8, 32 p., e3002217.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display
Rimbault, C., Knudsen, P. D., Damsbo, A., Boddum, K., Ali, H., Hackney, Celeste Menuet, Ellgaard, Lars, Bohn, M. & Laustsen, A. H., 2023, In: New Biotechnology. 76, p. 23-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus
Müller, E., Hackney, Celeste Menuet, Ellgaard, Lars & Morth, J. P., 2023, In: Acta crystallographica. Section F, Structural biology communications. 79, 9, p. 240-246 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Modern venomics - Current insights, novel methods, and future perspectives in biological and applied animal venom research
von Reumont, B. M., Anderluh, G., Antunes, A., Ayvazyan, N., Beis, D., Caliskan, F., Crnković, A., Damm, M., Dutertre, S., Ellgaard, L., Gajski, G., German, H., Halassy, B., Hempel, B-F., Hucho, T., Igci, N., Ikonomopoulou, M. P., Karbat, I., Klapa, M. I., Koludarov, I. & 15 others, , 2022, In: GigaScience. 11, 27 p., giac048.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of an Active, Human Membrane Protein in Saccharomyces cerevisiae: Full-Length FICD
Virolainen, M. S., Søltoft, C. L., Pedersen, Per Amstrup & Ellgaard, Lars, 2022, In: International Journal of Molecular Sciences. 23, 5, 17 p., 2458.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strategies for Heterologous Expression, Synthesis, and Purification of Animal Venom Toxins
Rivera-de-Torre, E., Rimbault, C., Jenkins, T. P., Sørensen, C. V., Damsbo, A., Saez, N. J., Duhoo, Y., Hackney, Celeste Menuet, Ellgaard, Lars & Laustsen, A. H., 2022, In: Frontiers in Bioengineering and Biotechnology. 9, 26 p., 811905.Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
DisCoTune: versatile auxiliary plasmids for the production of disulphide-containing proteins and peptides in the E. coli T7 system
Bertelsen, A. B., Hackney, Celeste Menuet, Bayer, C. N., Kjelgaard, L. D., Rennig, M., Christensen, B., Sørensen, E. S., Safavi, Helena, Wulff, T., Ellgaard, Lars & Nørholm, M. H. H., 2021, In: Microbial Biotechnology. 14, 6, p. 2566-2580 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research
Bjørn-Yoshimoto, Walden, Ramiro, Iris Bea L. , Yandell, M., McIntosh, J. M., Olivera, B. M., Ellgaard, Lars & Safavi, Helena, 2020, In: Biomedicines. 8, 8, 22 p., 235.Research output: Contribution to journal › Review › Research › peer-review
- 2019
- Published
Cellular functions and molecular mechanisms of non-lysine ubiquitination
McClellan, A. J., Laugesen, Sophie Heiden & Ellgaard, Lars, 2019, In: Open Biology. 9, 9, 16 p., 190147.Research output: Contribution to journal › Review › Research › peer-review
- Published
The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework
Nielsen, L. D., Foged, M. M., Albert, A., Bertelsen, A. B., Søltoft, C. L., Robinson, S. D., Petersen, S. V., Purcell, A. W., Olivera, B. M., Norton, R. S., Vasskog, T., Safavi, Helena, Teilum, Kaare & Ellgaard, Lars, 2019, In: The Journal of Biological Chemistry. 294, 22, p. 8745-8759Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
How are proteins reduced in the endoplasmic reticulum?
Ellgaard, Lars, Sevier, C. S. & Bulleid, N. J., Jan 2018, In: Trends in Biochemical Sciences. 43, 1, p. 32-43 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins
O'Brien, H., Kanemura, S., Okumura, M., Baskin, R. P., Bandyopadhyay, P. K., Olivera, B. M., Ellgaard, Lars, Inaba, K. & Safavi, Helena, 2018, In: International Journal of Molecular Sciences . 19, 11, 15 p., 3418.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolutionary Adaptations to Cysteine-rich Peptide Folding
Safavi, Helena, Foged, M. M. & Ellgaard, Lars, 2018, Oxidative Folding of Proteins: Basic Principles, Cellular Regulation and Engineering . Feige, M. J. (ed.). Royal Society of Chemistry, p. 99-128 30 p. (Chemical Biology, Vol. 9).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2016
- Published
Co- and post-translational protein folding in the ER
Ellgaard, Lars, McCaul, N., Chatsisvili, A. & Braakman, I., Jun 2016, In: Traffic (Malden). 17 , 6, p. 615-638 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Bioinformatics analysis identifies several intrinsically disordered human E3 ubiquitin-protein ligases
Boomsma, Wouter, Nielsen, S. V., Lindorff-Larsen, Kresten, Hartmann-Petersen, Rasmus & Ellgaard, Lars, 2016, In: PeerJ. 4, 18 p., e1725.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens
Timms, R. T., Menzies, S. A., Tchasovnikarova, I. A., Christensen, L. C., Williamson, J. C., Antrobus, R., Dougan, G., Ellgaard, Lars & Lehner, P. J., 2016, In: Nature Communications. 7, 10 p., 11786.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides
Safavi, Helena, Li, Q., Jackson, R. L., Song, A. S., Boomsma, Wouter, Bandyopadhyay, P. K., Gruber, C. W., Purcell, A. W., Yandell, M., Olivera, B. M. & Ellgaard, Lars, 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 12, p. 3227-3232 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Specialized insulin is used for chemical warfare by fish-hunting cone snails
Safavi, Helena, Gajewiak, J., Karanth, S., Robinson, S. D., Ueberheide, B., Douglass, A. D., Schlegel, A., Imperial, J. S., Watkins, M., Bandyopadhyay, P. K., Yandell, M., Li, Q., Purcell, A. W., Norton, R. S., Ellgaard, Lars & Olivera, B. M., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 6, p. 1743-1748 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262
Hansen, H. G., Søltoft, C. L., Schmidt, J. D., Birk, J., Appenzeller-Herzog, C. & Ellgaard, Lars, 2014, In: Bioscience Reports. 34, 2, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum
Ramming, T., Hansen, H. G., Nagata, K., Ellgaard, Lars & Appenzeller-Herzog, C., 2014, In: Free Radical Biology & Medicine. 70, p. 106-116 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Giftsnegle som medicinskabe
Safavi, Helena, Andersen, K. M. & Ellgaard, Lars, 2014, In: Aktuel Naturvidenskab. 2014, 2, p. 12-16 5 p.Research output: Contribution to journal › Journal article › Research
- Published
The selenium metabolite methylselenol regulates the expression of ligands that trigger immune activation through the lymphocyte receptor NKG2D
Hagemann-Jensen, M. H., Uhlenbrock, F. K., Kehlet, S., Andresen, Lars, Gabel-Jensen, C., Ellgaard, Lars, Gammelgaard, Bente & Skov, Søren, 2014, In: The Journal of Biological Chemistry. 289, p. 31576-31590 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin
Poulsen, E. G., Steinhauer, C., Lees, M., Lauridsen, A., Ellgaard, Lars & Hartmann-Petersen, Rasmus, 2012, In: P L o S One. 7, 11, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response
Hansen, H. G., Schmidt, J. D., Søltoft, C. L., Ramming, T., Geertz-Hansen, H. M., Christensen, B., Sørensen, E. S., Juncker, A., Appenzeller, C. A. & Ellgaard, Lars, 2012, In: Journal of Biological Chemistry. 287, 47, p. 39513-39523 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular chaperones in targeting misfolded proteins for ubiquitin-dependent degradation
Kriegenburg, F., Ellgaard, Lars & Hartmann-Petersen, Rasmus, 2012, In: F E B S Journal. 279, 4, p. 532-542 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HUWE1 and TRIP12 Collaborate in Degradation of Ubiquitin-Fusion Proteins and Misframed Ubiquitin
Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of the PDI-family member ERp90 as an interaction partner of ERFAD
Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262
Research output: Contribution to journal › Journal article › Research › peer-review
Published