Jens Vilstrup Johansen

Jens Vilstrup Johansen

Academic employee FU


  1. 2023
  2. Published

    An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions

    Radzisheuskaya, A., Peña-Rømer, I., Lorenzini, E., Koche, R., Zhan, Y., Shliaha, P. V., Cooper, A. J., Fan, Z., Shlyueva, D., Johansen, Jens Vilstrup, Hendrickson, R. C. & Helin, K., 2023, In: EMBO Journal. 42, 24, 22 p., e114221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    An organoid-based CRISPR-Cas9 screen for regulators of intestinal epithelial maturation and cell fate

    Hansen, Stine Lind, Larsen, Hjalte List, Pikkupeura, Laura Maarit, Maciag, Grzegorz Jerzy, Guiu, J., Müller, I., Clement, Ditte Lynge, Mueller, C., Johansen, Jens Vilstrup, Helin, K., Lerdrup, Mads & Jensen, Kim Bak, 2023, In: Science Advances. 9, 28, 18 p., eadg4055.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Distinct immune cell trigger responses in Ulcerative Colitis – Results from an in vivo human intestinal injury model

    Bronze, M., Johansen, Jens Vilstrup, Attauabi, M., Bjerrum, Jakob Tveiten , Ramírez Galera, Marina, Woetmann, Anders & Seidelin, Jakob Benedict, 2023, In: Journal of Crohn's and Colitis. 17, Supplement_1, p. i199-i200

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  5. 2021
  6. Published

    Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

    Seidelin, Jakob Benedict, Bahl, M. I., Licht, T. R., Mead, B. E., Karp, J. M., Johansen, Jens Vilstrup, Riis, Lene Buhl, Ramírez Galera, Marina, Woetmann, Anders & Bjerrum, Jakob Tveiten , 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 4, p. 1281-1296

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effects of a single dose of psilocybin on behaviour, brain 5-HT2A receptor occupancy and gene expression in the pig

    Donovan, L. L., Johansen, Jens Vilstrup, Ros, N. F., Jaberi, E., Linnet, Kristian, Johansen, Sys Stybe, Ozenne, Brice Maxime Hugues, Issazadeh-Navikas, Shohreh, Hansen, H. D. & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 42, p. 1-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2020
  9. Published

    KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes

    Sankar, A., Lerdrup, Mads, Manaf, A., Johansen, Jens Vilstrup, Martin Gonzalez, Javier, Borup, R., Blanshard, R., Klungland, A., Hansen, K., tcg964, tcg964, Dahl, J. A., Helin, K. & Hoffmann, Eva, 2020, In: Nature Cell Biology. 22, 4, p. 380-388 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mutations in a Single Signaling Pathway Allow Cell Growth in Heavy Water

    Kampmeyer, Caroline, Johansen, Jens Vilstrup, Holmberg, Christian, Karlson, M., Gersing, S. K., Nunes Bordallo, Heloisa, Kragelund, Birthe Brandt, Lerche, M. H., Jourdain, I., Winther, Jakob R. & Hartmann-Petersen, Rasmus, 2020, In: A C S Synthetic Biology. 9, 4, p. 733-748 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2019
  12. Published

    PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells

    Agrawal-Singh, S., Lerdrup, Mads, Gomes, A. R., van de Werken, H. J. G., Johansen, Jens Vilstrup, Andersson, Robin, Sandelin, Albin Gustav, Helin, K. & Hansen, K., 2019, In: eLife. 8, p. 1-32 32 p., e40364.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Tracing the cellular dynamics of sebaceous gland development in normal and perturbed states

    Andersen, M. S., Hannezo, E., Ulyanchenko, Svetlana, Estrach, S., Antoku, Yasuko, Pisano, S., Boonekamp, K. E., Sendrup, S., Maimets, Martti, Pedersen, M. T., Johansen, Jens Vilstrup, Clement, Ditte Lynge, Feral, C. C., Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature Cell Biology. 21, 8, p. 924-932

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2018
  15. Published

    YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration

    Yui, S., Azzolin, L., Maimets, Martti, Pedersen, M. T., Fordham, R. P., Hansen, Stine Lind, Larsen, Hjalte List, Guiu, J., Alves, M. R. P., Friis, Carsten, Johansen, Jens Vilstrup, Li, Yuan, Madsen, C. D., Nakamura, T., Watanabe, M., Nielsen, Ole Haagen, Schweiger, P. J., Piccolo, S. & Jensen, Kim Bak, 1 Jan 2018, In: Cell Stem Cell. 22, 1, p. 35-49. e7 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication

    Reveron-Gomez, Nazaret, González-Aguilera, C., Stewart-Morgan, Kathleen, Petryk, N., Flury, Valentin, Graziano, S., Johansen, Jens Vilstrup, Jakobsen, J. S., Alabert, C. & Groth, Anja, 2018, In: Molecular Cell. 72, 2, p. 239-249 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

    Shoaib, Muhammad, Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, Mads, Johansen, Jens Vilstrup, Hansen, K., Julien, E., Blow, J. J. & Sørensen, Claus Storgaard, 2018, In: Nature Communications. 9, 1, p. 1-11 11 p., 3704.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2017
  19. Published

    CRISPR/Cas9 Engineering of Adult Mouse Liver Demonstrates That the Dnajb1–Prkaca Gene Fusion Is Sufficient to Induce Tumors Resembling Fibrolamellar Hepatocellular Carcinoma

    Engelholm, Lars Henning, Riaz, A., Serra, Denise, Dagnæs-Hansen, F., Johansen, Jens Vilstrup, Santoni Rugiu, Eric, Hansen, S. H., Niola, Francesco & Frödin, Morten, 1 Dec 2017, In: Gastroenterology. 153, 6, p. 1662-1673.e10

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

    Mohammad, F., Weissmann, S., Leblanc, B. O., Pandey, D. P., Højfeldt, J. W., Comet, I., Zheng, C., Johansen, Jens Vilstrup, Rapin, N. P. J., Porse, Bo Torben, Tvardovskiy, A., Jensen, O. N., Olaciregui, N. G., Lavarino, C., Suñol, M., de Torres, C., Mora, J., Carcaboso, A. M. & Helin, K., Apr 2017, In: Nature Medicine. 23, 4, p. 483-492 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity

    Amendola, P. G., Zaghet, Nico, Ramalho, J. J., Johansen, Jens Vilstrup, Boxem, M. & Salcini, Anna Elisabetta, Feb 2017, In: P L o S Genetics. 13, 2, 24 p., e1006632.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    UBL/BAG-domain co-chaperones cause cellular stress upon overexpression through constitutive activation of Hsf1

    Poulsen, E. G., Kampmeyer, Caroline, Kriegenburg, F., Johansen, Jens Vilstrup, Hofmann, K., Holmberg, Christian & Hartmann-Petersen, Rasmus, Jan 2017, In: Cell Stress & Chaperones. 22, 1, p. 143-154 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2016
  24. Published

    Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

    Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, Jens Vilstrup, Hayward, D. G., Nilsson, Jakob, Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells

    Agger, K., Miyagi, S., Pedersen, M. T., Kooistra, S. M., Johansen, Jens Vilstrup & Helin, K., 1 Jun 2016, In: Genes & Development. 30, 11, p. 1278-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    An interactive environment for agile analysis and visualization of ChIP-sequencing data

    Lerdrup, Mads, Johansen, Jens Vilstrup, Agrawal-Singh, S. & Hansen, K., Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 349-57 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

    Feng, Y., Vlassis, A., Roques, C., Lalonde, M. E., Gonzalez Aguilera, C., Lambert, J. P., Lee, S., Zhao, X., Alabert, C., Johansen, Jens Vilstrup, Paquet, E., Yang, X. J., Gingras, A. C., Côté, J. & Groth, Anja, 2016, In: EMBO Journal. 35, 2, p. 176-192 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    High-throughput siRNA screening applied to the ubiquitin-proteasome system

    Poulsen, E. G., Nielsen, S. V., Pietras, E. J., Johansen, Jens Vilstrup, Steinhauer, C. & Hartmann-Petersen, Rasmus, 2016, Proteostasis. Matthiesen, R. (ed.). Springer, p. 421-439 19 p. (Methods in Molecular Biology, Vol. 1449).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  29. 2015
  30. Published

    Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis

    Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Pedersen, M. T., Rapin, N., Bagger, F. O., Porse, Bo Torben, Bernard, O. A., Christensen, J. & Helin, K., 17 Apr 2015, In: Genes & Development. p. 910-922 13 p., 29.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Loss of PRDM11 promotes MYC-driven lymphomagenesis

    Fog-Tonnesen, C. K., Asmar, F., Côme, Christophe Roger Michel, Jensen, K. T., Johansen, Jens Vilstrup, Bou Kheir, T., Jacobsen, L., Friis, C., Louw, A., Rosgaard, L., Øbro, N. F., Marquart, Hanne Vibeke Hansen, Anthonsen, K., Braat, A. K., van Lohuizen, M., Ralfkiaer, E., Grønbæk, Kirsten & Lund, Anders H., 19 Feb 2015, In: Blood. 125, 8, p. 1272-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Allele-Specific DNA Methylation Detection by Pyrosequencing®

    Sommer Kristensen, L., Johansen, Jens Vilstrup & Grønbæk, Kirsten, 2015, Pyrosequencing: Methods and Protocols. Lehmann, U. & Tost, J. (eds.). Vol. 1315. p. 271-89 19 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  33. Published

    Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

    Klein, D. K., Hoffmann, Saskia, Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, Brian Daniel, Rolland, B., Rösner, Heike Ilona, Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, Jens Vilstrup, Rappsilber, J., Engeland, K. & Sørensen, Claus Storgaard, 2015, In: Nature Communications. 6, p. 5800

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    SWI/SNF Subunits SMARCA4, SMARCD2 and DPF2 Collaborate in MLL-Rearranged Leukaemia Maintenance

    Cruickshank, V. A., Sroczynska, P., Sankar, A., Miyagi, S., Friis, Carsten, Johansen, Jens Vilstrup & Helin, K., 2015, In: PLOS ONE. 10, 11, p. e0142806

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2014
  36. Published

    Gene Silencing Triggers Polycomb Repressive Complex 2 Recruitment to CpG Islands Genome Wide

    Riising, E. M., Vacher-Comet, I., Leblanc, B. O., Wu, X., Johansen, Jens Vilstrup & Helin, K., 3 Jul 2014, In: Molecular Cell.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Demethylase JMJD2C Localizes to H3K4me3 Positive Transcription Start Sites and Is Dispensable for Embryonic Development

    Pedersen, M. T., Agger, K., Laugesen, A., Johansen, Jens Vilstrup, Cloos, P. A. C., Christensen, J. A. & Helin, K., 6 Jan 2014, In: Molecular and Cellular Biology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    A Screen Identifies the Oncogenic Micro-RNA miR-378a-5p as a Negative Regulator of Oncogene-Induced Senescence

    Kooistra, S. M., Rudkjær, L. C., Lees, M. J., Steinhauer, C., Johansen, Jens Vilstrup & Helin, K., 2014, In: PLOS ONE. 9, 3, p. 1-7 7 p., e91034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner

    Williams, K., Christensen, J., Rappsilber, J., Nielsen, A. L., Johansen, Jens Vilstrup & Helin, K., 2014, In: PLOS ONE. 9, 5, p. e96545

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2013
  41. Published

    Loss Of Tet2 Collaborates With AML1-ETO In Inducing Leukemogenesis

    Rasmussen, K. D., Jia, G., Johansen, Jens Vilstrup, Bernard, O. A. & Helin, K., 15 Nov 2013, In: Blood. 122, 21

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3

    Albert, M., Schmitz, S. U., Kooistra, S. M., Malatesta, M., Morales Torres, C., Rekling, Jens Christian, Johansen, Jens Vilstrup, Abarrategui, I. & Helin, K., Apr 2013, In: P L o S Genetics. 9, 4, p. 1-15 16 p., e1003461.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation

    Wu, X., Johansen, Jens Vilstrup & Helin, K., 28 Mar 2013, In: Molecular Cell. 49, 6, p. 1134-46 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. 2011
  45. Published

    TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity

    Williams, K., Christensen, J., Pedersen, M. T., Johansen, Jens Vilstrup, Cloos, P. A. C., Rappsilber, J. & Helin, K., 19 May 2011, In: Nature. 473, 7347, p. 343-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    A genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenance

    Menzel, T., Nähse-Kumpf, V., Kousholt, A. N., Klein, D. K., Lund-Andersen, C., Lees, M., Johansen, Jens Vilstrup, Syljuåsen, R. G. & Sørensen, Claus Storgaard, 1 Jan 2011, In: E M B O Reports. 12, 7, p. 705-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Jarid1b targets genes regulating development and is involved in neural differentiation

    Schmitz, S. U., Albert, M., Malatesta, M., Morey Ramonell, L., Johansen, Jens Vilstrup, Bak, M., Tommerup, Niels, Abarrategui Garcia, I. & Helin, K., 2011, In: E M B O Journal. 30, 22, p. 4586-600 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    MMSET is highly expressed and associated with aggressiveness in neuroblastoma

    Hudlebusch, H. R., Skotte, J., Santoni-Rugiu, E., Zimling, Z. G., Lees, M. J., Simon, R., Sauter, G., Rota, R., De Ioris, M. A., Quarto, M., Johansen, J. V., Jorgensen, M., Rechnitzer, C., Maroun, L. L., Schrøder, H., Petersen, B. L., Helin, K., Hudlebusch, H. R., Skotte, J., Santoni-Rugiu, E. & 14 others, Zimling, Z. G., Lees, M. J., Simon, R., Sauter, G., Rota, R., De Ioris, M. A., Quarto, M., Johansen, J. V., Jørgensen, M., Rechnitzer, C., Maroun, L. L., Schrøder, H., Petersen, B. L. & Helin, K., 2011, In: Cancer Research. 71, 12, p. 4226-35 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors

    Hudlebusch, H. R., Santoni-Rugiu, E., Simon, R., Ralfkiær, E., Rossing, H. H., Johansen, Jens Vilstrup, Jørgensen, M., Sauter, G. & Helin, K., 2011, In: Clinical Cancer Research. 17, 9, p. 2919-33 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. 2010
  51. Published

    JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

    Pasini, D., Cloos, P. A. C., Walfridsson, J., Olsson, L., Bukowski, J., Johansen, Jens Vilstrup, Bak, M., Tommerup, Niels, Rappsilber, J. & Helin, K., 2010, In: Nature. 464, 7286, p. 306-10 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2009
  53. Published

    RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells

    Doehn, U., Hauge, C., Frank, S. R., Jensen, C. A. J., Duda, K., Nielsen, J. V., Cohen, M. S., Johansen, Jens Vilstrup, Winther, B. R., Lund, L. R., Winther, Ole, Taunton, J., Hansen, S. H. & Frödin, Morten, 2009, In: Molecular Cell. 35, 4, p. 511-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2008
  55. Published

    Prediction of fat oxidation capacity using 1H-NMR and LC-MS lipid metabolomic data combined with phenotypic data

    Pers, T. H., Martin, F. P., Verdich, C., Holst, C., Johansen, Jens Vilstrup, Astrup, A., Polak, J., Martinez, J. A., Rezzi, S., Blaak, E. E., Saris, W. H. M., Kochhar, S., Macdonald, I. A., Sørensen, T. I. A. & Ramadan, Z., 2008, In: Chemometrics and Intelligent Laboratory Systems. 93, 1, p. 34-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13717