Holger Grohganz
Associate Professor
Solid State Pharmaceutics
Universitetsparken 2, 2100 København Ø
Pharmaceuticals, processes and products
Universitetsparken 2
2100 København Ø
- Published
Glass-Transition Temperature of the β-Relaxation as the Major Predictive Parameter for Recrystallization of Neat Amorphous Drugs
Kissi, E. O., Grohganz, Holger, Löbmann, Korbinian, Ruggiero, M. T., Zeitler, J. A. & Rades, Thomas, 15 Mar 2018, In: Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical. 122, 10, p. 2803-2808 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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INFLUENCE OF THE COOLING RATE AND THE BLEND RATIO ON THE PHYSICAL STABILTIY OF CO-AMORPHOUS NAPROXEN/INDOMETHACIN
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 13 Oct 2016, In: European Journal of Pharmaceutics and Biopharmaceutics. 109, p. 140-148 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Molecular Surface Diffusion on the Physical Stability of Co-Amorphous Systems
Liu, J., Hwu, E., Bannow, J., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 4, p. 1183-1190Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 30 Jun 2017, In: International Journal of Pharmaceutics. 526, 1-2, p. 88-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improving co-amorphous drug formulations by the addition of the highly water soluble amino acid proline
Jensen, K. B. T., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2014, In: Pharmaceutics. 6, 3, p. 416-435 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ amorphisation of indomethacin with Eudragit® E during dissolution
Priemel, P. A., Laitinen, R., Grohganz, Holger, Rades, Thomas & Strachan, C. J., Nov 2013, In: European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 Pt B, p. 1259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation in coated tablets – The combination of carvedilol with aspartic acid during immersion in an acidic medium
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 10 Mar 2019, In: International Journal of Pharmaceutics. 558, p. 357-366 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium – A proof of concept study
Petry, I., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Leopold, C. S., 1 Dec 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 133, p. 151-160 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro and in vivo comparison between crystalline and co-amorphous salts of naproxen-arginine
Kasten, G., Lobo, L., Dengale, S., Grohganz, Holger, Rades, Thomas & Löbmann, Korbinian, 1 Nov 2018, In: European Journal of Pharmaceutics and Biopharmaceutics. 132, p. 192-199 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of Glass Forming Ability on the Physical Stability of Supersaturated Amorphous Solid Dispersions
Blaabjerg, L. I., Bulduk, B., Lindenberg, E., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 1 Jan 2019, In: Journal of Pharmaceutical Sciences. 108, 8, p. 2561-2569Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of PVP molecular weight on the microwave assisted in situ amorphization of indomethacin
Doreth, M., Löbmann, Korbinian, Priemel, P., Grohganz, Holger, Taylor, R., Holm, R., Lopez de Diego, H. & Rades, Thomas, Jan 2018, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 122, p. 62-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Mishra, J., Rades, Thomas, Löbmann, Korbinian & Grohganz, Holger, 12 Apr 2018, In: Pharmaceutics. 10, 2, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Water on Amorphous Lidocaine
Xu, X., Grohganz, Holger & Rades, Thomas, 2022, In: Molecular Pharmaceutics. 19, 9, p. 3199–3205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of polymer addition on the amorphization, dissolution and physical stability of co-amorphous systems
Liu, J., Grohganz, Holger & Rades, Thomas, 2020, In: International Journal of Pharmaceutics. 588, p. 1-9 9 p., 119768.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of preparation pathway on the glass forming ability
Blaabjerg, L. I., Lindenberg, E., Rades, Thomas, Grohganz, Holger & Löbmann, Korbinian, 21 Apr 2017, In: International Journal of Pharmaceutics. 521, 1-2, p. 232-238Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of preparation technique on co-amorphization of carvedilol with acidic amino acids
Mishra, J., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Dec 2018, In: International Journal of Pharmaceutics. 552, 1-2, p. 407-413Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
Jensen, K. B. T., Larsen, F. H., Löbmann, Korbinian, Rades, Thomas & Grohganz, Holger, 2016, In: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 107, p. 32-39 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of water and trehalose on α- and β-relaxation of freeze-dried lysozyme formulations
Vallaster, B., Engelsing, F. & Grohganz, Holger, 2024, In: European Journal of Pharmaceutics and Biopharmaceutics. 194, p. 1-8Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures
Priemel, P. A., Laitinen, R., Barthold, S., Grohganz, Holger, Lehto, V., Rades, Thomas & Strachan, C. J., 18 Nov 2013, In: International Journal of Pharmaceutics. 456, 2, p. 301-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers
Bohsen, M. S., Tychsen, S. T., Kadhim, A. A. H., Grohganz, Holger, Treusch, A. H. & Brandl, M., 2023, In: European Journal of Pharmaceutical Sciences. 182, 10 p., 106384.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigation of physical properties and stability of indomethacin-cimetidine and naproxen-cimetidine co-amorphous systems prepared by quench cooling, coprecipitation and ball milling
Lim, A. W., Löbmann, Korbinian, Grohganz, Holger, Rades, Thomas & Chieng, N., Jan 2016, In: Journal of Pharmacy and Pharmacology. 68, 1, p. 36-45 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is there a correlation between the glass forming ability of a drug and its supersaturation propensity?
Blaabjerg, L. I., Lindenberg, E., Löbmann, Korbinian, Grohganz, Holger & Rades, Thomas, 1 Mar 2018, In: International Journal of Pharmaceutics. 538, 1-2, p. 243-249Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale biophysical evaluation of protein PEGylation effects: in vitro properties of 61 protein entities
Vernet, E., Popa, G., Pozdnyakova, I., Rasmussen, J. E., Grohganz, Holger, Giehm, L., Jensen, M. H., Wang, H., Plesner, B., Nielsen, Hanne Mørck, Jensen, Knud Jørgen, Berthelsen, J., Sundström, M. & van de Weert, Marco, 2016, In: Molecular Pharmaceutics. 13, 5, p. 1587-1598 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular interactions of hydrated co-amorphous systems of prilocaine and lidocaine
Xu, X., Rades, Thomas & Grohganz, Holger, 2024, In: International Journal of Pharmaceutics. 651, 7 p., 123807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multivariate Quantification of the Solid State Phase Composition of Co-Amorphous Naproxen-Indomethacin
Beyer, A., Grohganz, Holger, Löbmann, Korbinian, Rades, Thomas & Leopold, C. S., 2015, In: Molecules. 20, 10, p. 19571-87 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1421411
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The significance of the amorphous potential energy landscape for dictating glassy dynamics and driving solid-state crystallisation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
205
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Influence of Solvent Composition on the Performance of Spray-Dried Co-Amorphous Formulations
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
159
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The Influence of Polymers on the Supersaturation Potential of Poor and Good Glass Formers
Research output: Contribution to journal › Journal article › Research › peer-review
Published