Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia.

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia. / Gjedde, A; Hindfelt, B.

In: Acta Anaesthesiologica Scandinavica, Vol. 19, No. 4, 1975, p. 310-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Gjedde, A & Hindfelt, B 1975, 'Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia.', Acta Anaesthesiologica Scandinavica, vol. 19, no. 4, pp. 310-5.

APA

Gjedde, A., & Hindfelt, B. (1975). Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia. Acta Anaesthesiologica Scandinavica, 19(4), 310-5.

Vancouver

Gjedde A, Hindfelt B. Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia. Acta Anaesthesiologica Scandinavica. 1975;19(4):310-5.

Author

Gjedde, A ; Hindfelt, B. / Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia. In: Acta Anaesthesiologica Scandinavica. 1975 ; Vol. 19, No. 4. pp. 310-5.

Bibtex

@article{1234aa20b31511debc73000ea68e967b,
title = "Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia.",
abstract = "A recent modification of the Kety-Schmidt wash-out technique for 133xenon was used to measure whole-brain blood flow (CBF) and oxygen consumption (CMRO2) 1 to 4 hours after termination of halothane anesthesia in 15 Wistar rats. In this 3-hour experimental period, mean CBF and CMRO2 were reduced to 29 and 43% of control values, respectively. CBF and CMRO2 determined at the beginning and end of the experimental period were not significantly different from each other. Cerebral venous O2 tension was significantly higher than in the control group, supporting recent suggestions of a primary, intrinsic effect of halothane on the homeostatic control of this variable. It is concluded that halothane is not useful for cerebral metabolic studies in the rat.",
author = "A Gjedde and B Hindfelt",
year = "1975",
language = "English",
volume = "19",
pages = "310--5",
journal = "Acta Anaesthesiologica Scandinavica",
issn = "0001-5172",
publisher = "Wiley-Blackwell",
number = "4",

}

RIS

TY - JOUR

T1 - Whole-brain blood flow and oxygen metabolism in the rat after halothane anesthesia.

AU - Gjedde, A

AU - Hindfelt, B

PY - 1975

Y1 - 1975

N2 - A recent modification of the Kety-Schmidt wash-out technique for 133xenon was used to measure whole-brain blood flow (CBF) and oxygen consumption (CMRO2) 1 to 4 hours after termination of halothane anesthesia in 15 Wistar rats. In this 3-hour experimental period, mean CBF and CMRO2 were reduced to 29 and 43% of control values, respectively. CBF and CMRO2 determined at the beginning and end of the experimental period were not significantly different from each other. Cerebral venous O2 tension was significantly higher than in the control group, supporting recent suggestions of a primary, intrinsic effect of halothane on the homeostatic control of this variable. It is concluded that halothane is not useful for cerebral metabolic studies in the rat.

AB - A recent modification of the Kety-Schmidt wash-out technique for 133xenon was used to measure whole-brain blood flow (CBF) and oxygen consumption (CMRO2) 1 to 4 hours after termination of halothane anesthesia in 15 Wistar rats. In this 3-hour experimental period, mean CBF and CMRO2 were reduced to 29 and 43% of control values, respectively. CBF and CMRO2 determined at the beginning and end of the experimental period were not significantly different from each other. Cerebral venous O2 tension was significantly higher than in the control group, supporting recent suggestions of a primary, intrinsic effect of halothane on the homeostatic control of this variable. It is concluded that halothane is not useful for cerebral metabolic studies in the rat.

M3 - Journal article

C2 - 1189883

VL - 19

SP - 310

EP - 315

JO - Acta Anaesthesiologica Scandinavica

JF - Acta Anaesthesiologica Scandinavica

SN - 0001-5172

IS - 4

ER -

ID: 14944215