Ultrasound pathology of the entheses in an age and gender stratified sample of healthy adult subjects: a prospective cross-sectional frequency study
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Ultrasound pathology of the entheses in an age and gender stratified sample of healthy adult subjects : a prospective cross-sectional frequency study. / Guldberg-Møller, Jørgen; Terslev, Lene; Nielsen, Sabrina M; Kønig, Merete Juhl; Torp-Pedersen, Søren T; Torp-Pedersen, Arendse; Christensen, Robin; Bliddal, Henning; Ellegaard, Karen.
In: Clinical and Experimental Rheumatology, Vol. 37, No. 3, 2019, p. 408-413.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Ultrasound pathology of the entheses in an age and gender stratified sample of healthy adult subjects
T2 - a prospective cross-sectional frequency study
AU - Guldberg-Møller, Jørgen
AU - Terslev, Lene
AU - Nielsen, Sabrina M
AU - Kønig, Merete Juhl
AU - Torp-Pedersen, Søren T
AU - Torp-Pedersen, Arendse
AU - Christensen, Robin
AU - Bliddal, Henning
AU - Ellegaard, Karen
PY - 2019
Y1 - 2019
N2 - OBJECTIVES: Ultrasound (US) examination of the entheses is increasingly used. However, little is known about US findings in the entheses in asymptomatic persons. The aim of this study was to investigate the appearance of US signs in the enthuses of the lower limb in asymptomatic subjects.METHODS: We recruited 64 subjects, eight women and eight men whose ages covered four decades, from 20 to 60 years. None had tendon or joint disease in the lower limbs. Participants were examined by a rheumatologist and blood samples were collected to rule out enthesis pathology. The enthesis of the dominant leg were examined with grey-scale and Doppler US to evaluate increased thickness, changed structure, enthesophytes/calcifications, erosions, and colour Doppler signal.RESULTS: Ultrasound examination of 320 entheses was made. At enthesis level, elementary lesions were seen at 73 (22.8%) sites, at subject-level 47 (73.4%) persons showed elementary lesions, in 27 (57%) only one enthesis was affected. Doppler activity was seen in four sites, three at the quadriceps insertion. Most common US elementary lesion was enthesophytes at the Achilles and quadriceps tendon insertion. A tendency towards more elementary lesions was seen in men, and a slight increase was seen with increasing age, however, not statistically significance.CONCLUSIONS: Our findings suggest that US can be used to diagnose/examine subjects in adulthood for pathological changes in the entheses; however, caution should be taken regarding enthesophytes of the quadriceps and Achilles tendon.
AB - OBJECTIVES: Ultrasound (US) examination of the entheses is increasingly used. However, little is known about US findings in the entheses in asymptomatic persons. The aim of this study was to investigate the appearance of US signs in the enthuses of the lower limb in asymptomatic subjects.METHODS: We recruited 64 subjects, eight women and eight men whose ages covered four decades, from 20 to 60 years. None had tendon or joint disease in the lower limbs. Participants were examined by a rheumatologist and blood samples were collected to rule out enthesis pathology. The enthesis of the dominant leg were examined with grey-scale and Doppler US to evaluate increased thickness, changed structure, enthesophytes/calcifications, erosions, and colour Doppler signal.RESULTS: Ultrasound examination of 320 entheses was made. At enthesis level, elementary lesions were seen at 73 (22.8%) sites, at subject-level 47 (73.4%) persons showed elementary lesions, in 27 (57%) only one enthesis was affected. Doppler activity was seen in four sites, three at the quadriceps insertion. Most common US elementary lesion was enthesophytes at the Achilles and quadriceps tendon insertion. A tendency towards more elementary lesions was seen in men, and a slight increase was seen with increasing age, however, not statistically significance.CONCLUSIONS: Our findings suggest that US can be used to diagnose/examine subjects in adulthood for pathological changes in the entheses; however, caution should be taken regarding enthesophytes of the quadriceps and Achilles tendon.
KW - Achilles Tendon
KW - Adult
KW - Cartilage, Articular/diagnostic imaging
KW - Cross-Sectional Studies
KW - Female
KW - Fibrocartilage/diagnostic imaging
KW - Humans
KW - Male
KW - Middle Aged
KW - Prospective Studies
KW - Tendons/diagnostic imaging
KW - Ultrasonography/methods
KW - Ultrasonography, Doppler
KW - Young Adult
M3 - Journal article
C2 - 30620269
VL - 37
SP - 408
EP - 413
JO - Clinical and Experimental Rheumatology
JF - Clinical and Experimental Rheumatology
SN - 0392-856X
IS - 3
ER -
ID: 238486698