Treatment of first-episode psychosis patient, psychosocial aspects

Research output: Contribution to journal › Review › Research › peer-review

Standard

Treatment of first-episode psychosis patient, psychosocial aspects. / Nordentoft, Merete; Austin, Stephen; Bertelsen, Mette; Jeppesen, Pia; Jørgensen, Per; Melau, Marianne; Petersen, Lone; Secher, Gry; Thorup, Anne.

In: Drug Discovery Today: Therapeutic Strategies, Vol. 8, No. 1-2, 01.06.2011, p. 37-41.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Nordentoft, M, Austin, S, Bertelsen, M, Jeppesen, P, Jørgensen, P, Melau, M, Petersen, L, Secher, G & Thorup, A 2011, 'Treatment of first-episode psychosis patient, psychosocial aspects', Drug Discovery Today: Therapeutic Strategies, vol. 8, no. 1-2, pp. 37-41. https://doi.org/10.1016/j.ddstr.2011.10.006

APA

Nordentoft, M., Austin, S., Bertelsen, M., Jeppesen, P., Jørgensen, P., Melau, M., Petersen, L., Secher, G., & Thorup, A. (2011). Treatment of first-episode psychosis patient, psychosocial aspects. Drug Discovery Today: Therapeutic Strategies, 8(1-2), 37-41. https://doi.org/10.1016/j.ddstr.2011.10.006

Vancouver

Nordentoft M, Austin S, Bertelsen M, Jeppesen P, Jørgensen P, Melau M et al. Treatment of first-episode psychosis patient, psychosocial aspects. Drug Discovery Today: Therapeutic Strategies. 2011 Jun 1;8(1-2):37-41. https://doi.org/10.1016/j.ddstr.2011.10.006

Author

Nordentoft, Merete ; Austin, Stephen ; Bertelsen, Mette ; Jeppesen, Pia ; Jørgensen, Per ; Melau, Marianne ; Petersen, Lone ; Secher, Gry ; Thorup, Anne. / Treatment of first-episode psychosis patient, psychosocial aspects. In: Drug Discovery Today: Therapeutic Strategies. 2011 ; Vol. 8, No. 1-2. pp. 37-41.

Bibtex

@article{8e64b72b755e4f93bafba854d4840d76,
title = "Treatment of first-episode psychosis patient, psychosocial aspects",
abstract = "Two large randomised clinical trials, the OPUS and the LEO trials, investigating specialised assertive intensive treatment in early phases of psychosis have been shown to have positive effects on clinical symptoms, substance abuse, and user satisfaction although only some of these positive effects are sustainable over time. At a five-year follow-up, there were no clinical differences between the specialised assertive intervention group and standard care, but significantly more intervention patients were able to live independently and spent significantly fewer days in hospital. As a consequence of these outcomes, a comparison of five years and two years of specialised assertive treatment is currently being undertaken. Crucial elements in specialised assertive intensive treatment are the assertive approach and family involvement, and there is also some evidence supporting the inclusion of cognitive behavioural therapy, supported employment and weight management.",
author = "Merete Nordentoft and Stephen Austin and Mette Bertelsen and Pia Jeppesen and Per J{\o}rgensen and Marianne Melau and Lone Petersen and Gry Secher and Anne Thorup",
year = "2011",
month = jun,
day = "1",
doi = "10.1016/j.ddstr.2011.10.006",
language = "English",
volume = "8",
pages = "37--41",
journal = "Drug Discovery Today: Therapeutic Strategies",
issn = "1740-6773",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Treatment of first-episode psychosis patient, psychosocial aspects

AU - Nordentoft, Merete

AU - Austin, Stephen

AU - Bertelsen, Mette

AU - Jeppesen, Pia

AU - Jørgensen, Per

AU - Melau, Marianne

AU - Petersen, Lone

AU - Secher, Gry

AU - Thorup, Anne

PY - 2011/6/1

Y1 - 2011/6/1

N2 - Two large randomised clinical trials, the OPUS and the LEO trials, investigating specialised assertive intensive treatment in early phases of psychosis have been shown to have positive effects on clinical symptoms, substance abuse, and user satisfaction although only some of these positive effects are sustainable over time. At a five-year follow-up, there were no clinical differences between the specialised assertive intervention group and standard care, but significantly more intervention patients were able to live independently and spent significantly fewer days in hospital. As a consequence of these outcomes, a comparison of five years and two years of specialised assertive treatment is currently being undertaken. Crucial elements in specialised assertive intensive treatment are the assertive approach and family involvement, and there is also some evidence supporting the inclusion of cognitive behavioural therapy, supported employment and weight management.

AB - Two large randomised clinical trials, the OPUS and the LEO trials, investigating specialised assertive intensive treatment in early phases of psychosis have been shown to have positive effects on clinical symptoms, substance abuse, and user satisfaction although only some of these positive effects are sustainable over time. At a five-year follow-up, there were no clinical differences between the specialised assertive intervention group and standard care, but significantly more intervention patients were able to live independently and spent significantly fewer days in hospital. As a consequence of these outcomes, a comparison of five years and two years of specialised assertive treatment is currently being undertaken. Crucial elements in specialised assertive intensive treatment are the assertive approach and family involvement, and there is also some evidence supporting the inclusion of cognitive behavioural therapy, supported employment and weight management.

UR - http://www.scopus.com/inward/record.url?scp=84862158118&partnerID=8YFLogxK

U2 - 10.1016/j.ddstr.2011.10.006

DO - 10.1016/j.ddstr.2011.10.006

M3 - Review

AN - SCOPUS:84862158118

VL - 8

SP - 37

EP - 41

JO - Drug Discovery Today: Therapeutic Strategies

JF - Drug Discovery Today: Therapeutic Strategies

SN - 1740-6773

IS - 1-2

ER -

ID: 375016129