Transcription repair coupling factor: A very pushy enzyme
Research output: Contribution to journal › Review › Research › peer-review
An irreversibly stalled RNA polymerase (RNAP) in the coding region of an active gene blocks transcription and can lead to the loss of genome integrity. A recent study of the bacterial Mfd protein (Park et al., 2002 [Cell volume 109]) provides new insight into mechanisms that release RNAP from sites of arrest such as noncoding DNA lesions.
Original language | English |
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Journal | Molecular Cell |
Volume | 9 |
Issue number | 6 |
Pages (from-to) | 1151-1152 |
Number of pages | 2 |
ISSN | 1097-2765 |
DOIs | |
Publication status | Published - 2002 |
Externally published | Yes |
ID: 331042933