The RNA polymerase II transcription cycle: Cycling through chromatin

Research output: Contribution to journal › Review › Research › peer-review

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The RNA polymerase II transcription cycle : Cycling through chromatin. / Svejstrup, Jesper Q.

In: Biochimica et Biophysica Acta - Gene Structure and Expression, Vol. 1677, No. 1-3, 15.03.2004, p. 64-73.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Svejstrup, JQ 2004, 'The RNA polymerase II transcription cycle: Cycling through chromatin', Biochimica et Biophysica Acta - Gene Structure and Expression, vol. 1677, no. 1-3, pp. 64-73. https://doi.org/10.1016/j.bbaexp.2003.10.012

APA

Svejstrup, J. Q. (2004). The RNA polymerase II transcription cycle: Cycling through chromatin. Biochimica et Biophysica Acta - Gene Structure and Expression, 1677(1-3), 64-73. https://doi.org/10.1016/j.bbaexp.2003.10.012

Vancouver

Svejstrup JQ. The RNA polymerase II transcription cycle: Cycling through chromatin. Biochimica et Biophysica Acta - Gene Structure and Expression. 2004 Mar 15;1677(1-3):64-73. https://doi.org/10.1016/j.bbaexp.2003.10.012

Author

Svejstrup, Jesper Q. / The RNA polymerase II transcription cycle : Cycling through chromatin. In: Biochimica et Biophysica Acta - Gene Structure and Expression. 2004 ; Vol. 1677, No. 1-3. pp. 64-73.

Bibtex

@article{ebafe87314164f5f8659c9e9bfae1878,
title = "The RNA polymerase II transcription cycle: Cycling through chromatin",
abstract = "The cycle of events that characterizes RNA polymerase II transcription has been the focus of intense study over the past two decades. Our knowledge of the molecular processes leading to transcriptional initiation is greatly improved, and the focus of many recent studies has shifted towards the less well-characterized events taking place after assembly of the pre-initiation complex, such as promoter clearance, elongation, and termination. This review gives a brief overview of the transcription cycle as a whole, focusing especially on selected mechanisms that may drive or restrict the cycle, and on how the presence of chromatin may influence these mechanisms.",
keywords = "C-terminal domain (CTD), Promoter clearance, RNA processing, Transcript elongation, Transcription cycle",
author = "Svejstrup, {Jesper Q.}",
note = "Funding Information: Work in my laboratory is supported by grants from Cancer Research UK and the European Union (HPRN-CT-2000-00087). I apologise to colleagues whose work, due to the anecdotal character of this review, was not cited. ",
year = "2004",
month = mar,
day = "15",
doi = "10.1016/j.bbaexp.2003.10.012",
language = "English",
volume = "1677",
pages = "64--73",
journal = "Biochimica et Biophysica Acta, Gene Structure and Expression",
issn = "0167-4781",
publisher = "Elsevier Science",
number = "1-3",

}

RIS

TY - JOUR

T1 - The RNA polymerase II transcription cycle

T2 - Cycling through chromatin

AU - Svejstrup, Jesper Q.

N1 - Funding Information: Work in my laboratory is supported by grants from Cancer Research UK and the European Union (HPRN-CT-2000-00087). I apologise to colleagues whose work, due to the anecdotal character of this review, was not cited.

PY - 2004/3/15

Y1 - 2004/3/15

N2 - The cycle of events that characterizes RNA polymerase II transcription has been the focus of intense study over the past two decades. Our knowledge of the molecular processes leading to transcriptional initiation is greatly improved, and the focus of many recent studies has shifted towards the less well-characterized events taking place after assembly of the pre-initiation complex, such as promoter clearance, elongation, and termination. This review gives a brief overview of the transcription cycle as a whole, focusing especially on selected mechanisms that may drive or restrict the cycle, and on how the presence of chromatin may influence these mechanisms.

AB - The cycle of events that characterizes RNA polymerase II transcription has been the focus of intense study over the past two decades. Our knowledge of the molecular processes leading to transcriptional initiation is greatly improved, and the focus of many recent studies has shifted towards the less well-characterized events taking place after assembly of the pre-initiation complex, such as promoter clearance, elongation, and termination. This review gives a brief overview of the transcription cycle as a whole, focusing especially on selected mechanisms that may drive or restrict the cycle, and on how the presence of chromatin may influence these mechanisms.

KW - C-terminal domain (CTD)

KW - Promoter clearance

KW - RNA processing

KW - Transcript elongation

KW - Transcription cycle

U2 - 10.1016/j.bbaexp.2003.10.012

DO - 10.1016/j.bbaexp.2003.10.012

M3 - Review

C2 - 15020047

AN - SCOPUS:1542328272

VL - 1677

SP - 64

EP - 73

JO - Biochimica et Biophysica Acta, Gene Structure and Expression

JF - Biochimica et Biophysica Acta, Gene Structure and Expression

SN - 0167-4781

IS - 1-3

ER -

ID: 331040927