The absorption of natural vitamin c in horses and anti-oxidative capacity: A randomised, controlled study on trotters during a three-month intervention period
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The absorption of natural vitamin c in horses and anti-oxidative capacity : A randomised, controlled study on trotters during a three-month intervention period. / Winther, Kaj; Kharazmi, Arsalan; Hansen, Anne Sophie Vinther; Falk-Rønne, J.
In: Comparative Exercise Physiology, Vol. 8, No. 3-4, 2012, p. 195-201.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The absorption of natural vitamin c in horses and anti-oxidative capacity
T2 - A randomised, controlled study on trotters during a three-month intervention period
AU - Winther, Kaj
AU - Kharazmi, Arsalan
AU - Hansen, Anne Sophie Vinther
AU - Falk-Rønne, J
PY - 2012
Y1 - 2012
N2 - The primary aim of the present study was to assess whether low dose vitamin C supplemented in its natural form, as a dried powder from selected subspecies of rosehip (Rosa canina), would result in a detectable increase in the concentration of blood vitamin C in horses supplemented daily for three months. In a secondary part of the study, the anti-oxidant capacity of the present treatment was also tested. Sixteen horses were randomly allocated to two groups and supplemented with either 25 g rosehip powder daily (equal to 125 mg natural vitamin C), or with 50 gram rosehip powder daily (equal to 250 mg vitamin C). Serum vitamin C was analysed both prior to supplementation and then again 14, 28 and 84 days following supplementation. Anti-oxidative capacity was assessed as the release of oxidative anions from polymorph-nucleated leucocytes prior to supplementation and after 14 and 84 days, respectively. Whilst there was a trend towards an increase in serum vitamin C concentration following 84 days of supplementation with 125 mg of natural vitamin C, this was not statistically significant. However, a significant increase in serum vitamin C concentration was observed following 14 days of supplementation with 250 mg vitamin C (P < 0.02). The magnitude of this increase was greater following 28 and 84 days of supplementation (P < 0.02 and P < 0.02), respectively. Additionally, serum vitamin C concentration was significantly higher following supplementation with 250 versus 125 mg of vitamin C daily (P < 0.03). The higher dose of natural vitamin C also resulted in a significant reduction in the release of oxidative anions (P < 0.001). These results suggest that natural vitamin C from rosehip is absorbed sufficiently to raise serum vitamin C concentration and to reduce the liberation of oxidative anions in horses supplemented with less than 500 mg daily.
AB - The primary aim of the present study was to assess whether low dose vitamin C supplemented in its natural form, as a dried powder from selected subspecies of rosehip (Rosa canina), would result in a detectable increase in the concentration of blood vitamin C in horses supplemented daily for three months. In a secondary part of the study, the anti-oxidant capacity of the present treatment was also tested. Sixteen horses were randomly allocated to two groups and supplemented with either 25 g rosehip powder daily (equal to 125 mg natural vitamin C), or with 50 gram rosehip powder daily (equal to 250 mg vitamin C). Serum vitamin C was analysed both prior to supplementation and then again 14, 28 and 84 days following supplementation. Anti-oxidative capacity was assessed as the release of oxidative anions from polymorph-nucleated leucocytes prior to supplementation and after 14 and 84 days, respectively. Whilst there was a trend towards an increase in serum vitamin C concentration following 84 days of supplementation with 125 mg of natural vitamin C, this was not statistically significant. However, a significant increase in serum vitamin C concentration was observed following 14 days of supplementation with 250 mg vitamin C (P < 0.02). The magnitude of this increase was greater following 28 and 84 days of supplementation (P < 0.02 and P < 0.02), respectively. Additionally, serum vitamin C concentration was significantly higher following supplementation with 250 versus 125 mg of vitamin C daily (P < 0.03). The higher dose of natural vitamin C also resulted in a significant reduction in the release of oxidative anions (P < 0.001). These results suggest that natural vitamin C from rosehip is absorbed sufficiently to raise serum vitamin C concentration and to reduce the liberation of oxidative anions in horses supplemented with less than 500 mg daily.
KW - Antioxidants
KW - Dietary supplements
KW - Horses
KW - Rosehip
KW - Vitamin C
U2 - 10.3920/CEP12006
DO - 10.3920/CEP12006
M3 - Journal article
AN - SCOPUS:84928403042
VL - 8
SP - 195
EP - 201
JO - Comparative Exercise Physiology
JF - Comparative Exercise Physiology
SN - 1755-2540
IS - 3-4
ER -
ID: 211947623