Stroke rehabilitation at home before and after discharge reduced disability and improved quality of life: a randomised controlled trial
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Stroke rehabilitation at home before and after discharge reduced disability and improved quality of life : a randomised controlled trial. / Rasmussen, Rune Skovgaard; Østergaard, Ann; Kjær, Pia; Skerris, Anja; Skou, Christina T.; Christoffersen, Jane; Seest, Line Skou; Poulsen, Mai Bang; Rønholt, Finn; Overgaard, Karsten.
In: Clinical Rehabilitation, Vol. 30, No. 3, 03.2016, p. 225-236.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Stroke rehabilitation at home before and after discharge reduced disability and improved quality of life
T2 - a randomised controlled trial
AU - Rasmussen, Rune Skovgaard
AU - Østergaard, Ann
AU - Kjær, Pia
AU - Skerris, Anja
AU - Skou, Christina T.
AU - Christoffersen, Jane
AU - Seest, Line Skou
AU - Poulsen, Mai Bang
AU - Rønholt, Finn
AU - Overgaard, Karsten
N1 - © The Author(s) 2015.
PY - 2016/3
Y1 - 2016/3
N2 - OBJECTIVE: To evaluate if home-based rehabilitation of inpatients improved outcome compared to standard care.DESIGN: Interventional, randomised, safety/efficacy open-label trial.SETTING: University hospital stroke unit in collaboration with three municipalities.SUBJECTS: Seventy-one eligible stroke patients (41 women) with focal neurological deficits hospitalised in a stroke unit for more than three days and in need of rehabilitation.INTERVENTIONS: Thirty-eight patients were randomised to home-based rehabilitation during hospitalization and for up to four weeks after discharge to replace part of usual treatment and rehabilitation services. Thirty-three control patients received treatment and rehabilitation following usual guidelines for the treatment of stroke patients.MAIN MEASURES: Ninety days post-stroke the modified Rankin Scale score was the primary endpoint. Other outcome measures were the modified Barthel-100 Index, Motor Assessment Scale, CT-50 Cognitive Test, EuroQol-5D, Body Mass Index and treatment-associated economy.RESULTS: Thirty-one intervention and 30 control patients completed the study. Patients in the intervention group achieved better modified Rankin Scale score (Intervention median = 2, IQR = 2-3; Control median = 3, IQR = 2-4; P=0.04). EuroQol-5D quality of life median scores were improved in intervention patients (Intervention median = 0.77, IQR = 0.66-0.79; Control median = 0.66, IQR = 0.56 - 0.72; P=0.03). The total amount of home-based training in minutes highly correlated with mRS, Barthel, Motor Assessment Scale and EuroQol-5D™ scores (P-values ranging from P<0.00001 to P=0.01). Economical estimations of intervention costs were lower than total costs of standard treatment.CONCLUSION: Early home-based rehabilitation reduced disability and increased quality of life. Compared to standard care, home-based stroke rehabilitation was more cost-effective.
AB - OBJECTIVE: To evaluate if home-based rehabilitation of inpatients improved outcome compared to standard care.DESIGN: Interventional, randomised, safety/efficacy open-label trial.SETTING: University hospital stroke unit in collaboration with three municipalities.SUBJECTS: Seventy-one eligible stroke patients (41 women) with focal neurological deficits hospitalised in a stroke unit for more than three days and in need of rehabilitation.INTERVENTIONS: Thirty-eight patients were randomised to home-based rehabilitation during hospitalization and for up to four weeks after discharge to replace part of usual treatment and rehabilitation services. Thirty-three control patients received treatment and rehabilitation following usual guidelines for the treatment of stroke patients.MAIN MEASURES: Ninety days post-stroke the modified Rankin Scale score was the primary endpoint. Other outcome measures were the modified Barthel-100 Index, Motor Assessment Scale, CT-50 Cognitive Test, EuroQol-5D, Body Mass Index and treatment-associated economy.RESULTS: Thirty-one intervention and 30 control patients completed the study. Patients in the intervention group achieved better modified Rankin Scale score (Intervention median = 2, IQR = 2-3; Control median = 3, IQR = 2-4; P=0.04). EuroQol-5D quality of life median scores were improved in intervention patients (Intervention median = 0.77, IQR = 0.66-0.79; Control median = 0.66, IQR = 0.56 - 0.72; P=0.03). The total amount of home-based training in minutes highly correlated with mRS, Barthel, Motor Assessment Scale and EuroQol-5D™ scores (P-values ranging from P<0.00001 to P=0.01). Economical estimations of intervention costs were lower than total costs of standard treatment.CONCLUSION: Early home-based rehabilitation reduced disability and increased quality of life. Compared to standard care, home-based stroke rehabilitation was more cost-effective.
U2 - 10.1177/0269215515575165
DO - 10.1177/0269215515575165
M3 - Journal article
C2 - 25758941
VL - 30
SP - 225
EP - 236
JO - Clinical Rehabilitation
JF - Clinical Rehabilitation
SN - 0269-2155
IS - 3
ER -
ID: 162852617