Stimulation af knogleheling med vaekstfaktorer inden for ortopaedkirurgien
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Stimulation af knogleheling med vaekstfaktorer inden for ortopaedkirurgien. / Lind, M C; Laursen, M; Jensen, T B; Overgaard, S; Søballe, K; Bünger, C E.
In: Ugeskrift for Laeger, Vol. 162, No. 47, 20.11.2000, p. 6399-403.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Stimulation af knogleheling med vaekstfaktorer inden for ortopaedkirurgien
AU - Lind, M C
AU - Laursen, M
AU - Jensen, T B
AU - Overgaard, S
AU - Søballe, K
AU - Bünger, C E
PY - 2000/11/20
Y1 - 2000/11/20
N2 - Growth factors with specific effects on bone cells have been known of for more than a decade. Clinical usage of growth factors has recently become possible due to recombinant gene technology. In vivo studies over the last five years have demonstrated that growth factors can stimulate bone formation and bone healing and these results have made growth factors candidates for future clinical use in orthopaedic surgery. Growth factors for clinical use will become commercially available in the near future. The aim of this review paper is to describe the most important growth factors with effect on bone tissue and to give an updated review on experimental and clinical data on growth factor mediated bone healing in situations related to orthopaedic surgery. Possible areas for future clinical usage of growth factors are also discussed.
AB - Growth factors with specific effects on bone cells have been known of for more than a decade. Clinical usage of growth factors has recently become possible due to recombinant gene technology. In vivo studies over the last five years have demonstrated that growth factors can stimulate bone formation and bone healing and these results have made growth factors candidates for future clinical use in orthopaedic surgery. Growth factors for clinical use will become commercially available in the near future. The aim of this review paper is to describe the most important growth factors with effect on bone tissue and to give an updated review on experimental and clinical data on growth factor mediated bone healing in situations related to orthopaedic surgery. Possible areas for future clinical usage of growth factors are also discussed.
M3 - Tidsskriftartikel
C2 - 11116450
VL - 162
SP - 6399
EP - 6403
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 47
ER -
ID: 252048978