Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter?

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter? / Penny, Jeannette Østergaard; Overgaard, Søren.

In: Journal of Biomedical Materials Research, Vol. 92, No. 1, 01.01.2010, p. 1-4.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Penny, JØ & Overgaard, S 2010, 'Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter?', Journal of Biomedical Materials Research, vol. 92, no. 1, pp. 1-4.

APA

Penny, J. Ø., & Overgaard, S. (2010). Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter? Journal of Biomedical Materials Research, 92(1), 1-4.

Vancouver

Penny JØ, Overgaard S. Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter? Journal of Biomedical Materials Research. 2010 Jan 1;92(1):1-4.

Author

Penny, Jeannette Østergaard ; Overgaard, Søren. / Serum Chrome levels sampled with steel needle vs. plastic IV cannula. Does method matter?. In: Journal of Biomedical Materials Research. 2010 ; Vol. 92, No. 1. pp. 1-4.

Bibtex

@article{71c8009710004bcfb0f9737b929bca29,
title = "Serum Chrome levels sampled with steel needle vs. plastic IV cannula.: Does method matter?",
abstract = "  Modern Metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory.Method: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. Results: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. Conclusion: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.",
author = "Penny, {Jeannette {\O}stergaard} and S{\o}ren Overgaard",
year = "2010",
month = jan,
day = "1",
language = "English",
volume = "92",
pages = "1--4",
journal = "Journal of Biomedical Materials Research",
issn = "0021-9304",
publisher = "John Wiley & Sons, Ltd",
number = "1",

}

RIS

TY - JOUR

T1 - Serum Chrome levels sampled with steel needle vs. plastic IV cannula.

T2 - Does method matter?

AU - Penny, Jeannette Østergaard

AU - Overgaard, Søren

PY - 2010/1/1

Y1 - 2010/1/1

N2 -   Modern Metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory.Method: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. Results: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. Conclusion: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.

AB -   Modern Metal-on-metal (MoM) joint articulations releases metal ions to the body. Research tries to establish how much this elevates metal ion levels and whether it causes adverse effects. The steel needle that samples the blood may introduce additional chromium to the sample thereby causing bias. This study aimed to test that theory.Method: We compared serum chromium values for two sampling methods, steel needle and IV plastic cannula, as well as sampling sequence in 16 healthy volunteers. Results: We found statistically significant chromium contamination from the steel needle with mean differences between the two methods of 0.073 ng/mL, for the first sample, and 0.033 ng/mL for the second. No difference was found between the first and second plastic sample. The first steel needle sample contained an average of 0.047 ng/mL more than the second. This difference was only borderline significant. Conclusion: The chromium contamination from the steel needle is low, and sampling method matters little in MoM populations. If using steel needles we suggest discarding the first sample.

M3 - Journal article

VL - 92

SP - 1

EP - 4

JO - Journal of Biomedical Materials Research

JF - Journal of Biomedical Materials Research

SN - 0021-9304

IS - 1

ER -

ID: 252048826