TY - JOUR

T1 - Self-Help Plus para Refugiados y solicitantes de asilo

T2 - Protocolo de Estudio para una serie de Meta-análisis de datos de participantes individuales

AU - Karyotaki, Eirini

AU - Sijbrandij, Marit

AU - Purgato, Marianna

AU - Acarturk, Ceren

AU - Lakin, Daniel

AU - Bailey, Della

AU - Peckham, Emily

AU - Uygun, Ersin

AU - Tedeschi, Federico

AU - Wancata, Johannes

AU - Augustinavicius, Jura

AU - Carswell, Ken

AU - Välimäki, Maritta

AU - van Ommeren, Mark

AU - Koesters, Markus

AU - Popa, Mariana

AU - Leku, Marx Ronald

AU - Anttila, Minna

AU - Churchill, Rachel

AU - White, Ross

AU - Al-Hashimi, Sarah

AU - Lantta, Tella

AU - Au, Teresa

AU - Klein, Thomas

AU - Tol, Wietse A.

AU - Cuijpers, Pim

AU - Barbui, Corrado

N1 - Publisher Copyright: © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

PY - 2021

Y1 - 2021

N2 - Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.

AB - Background: Refugees and asylum seekers face various stressors due to displacement and are especially vulnerable to common mental disorders. To effectively manage psychological distress in this population, innovative interventions are required. The World Health Organization (WHO) Self-Help Plus (SH+) intervention has shown promising outcomes in reducing symptoms of common mental disorders among refugees and asylum seekers. However, individual participant differences in response to SH+ remain largely unknown. The Individual Participant Data (IPD) meta-analysis synthesizes raw datasets of trials to provide cutting-edge evidence of outcomes that cannot be examined by conventional meta-analytic approaches. Objectives: This protocol outlines the methods of a series of IPD meta-analyses aimed at examining the effects and potential moderators of SH+ in (a) reducing depressive symptoms at post-intervention and (b) preventing the six-month cumulative incidence of mental disorders in refugees and asylum seekers. Method: RCTs on SH+ have been identified through WHO and all authors have agreed to share the datasets of the trials. The primary outcomes of the IPD meta-analyses are (a) reduction in depressive symptoms at post-intervention, and (b) prevention of six-month cumulative incidence of mental disorders. Secondary outcomes include post-traumatic stress disorder symptoms, well-being, functioning, quality of life, and twelve-month cumulative incidence of mental disorders. One-stage IPD meta-analyses will be performed using mixed-effects linear/logistic regression. Missing data will be handled by multiple imputation. Conclusions: These results will enrich current knowledge about the response to SH+ and will facilitate its targeted dissemination. The results of these IPD meta-analyses will be published in peer-reviewed journals.

KW - asylum seekers

KW - common mental disorders

KW - depression

KW - individual participant data

KW - Refugees

U2 - 10.1080/20008198.2021.1930690

DO - 10.1080/20008198.2021.1930690

M3 - Journal article

C2 - 34262667

AN - SCOPUS:85109183560

VL - 12

JO - European Journal of Psychotraumatology

JF - European Journal of Psychotraumatology

SN - 2000-8198

IS - 1

M1 - 1930690

ER -