Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder : the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study. / Ellersgaard, Ditte; Gregersen, Maja; Ranning, Anne; Haspang, Thilde M; Christiani, Camilla; Hemager, Nicoline; Burton, Birgitte Klee; Spang, Katrine Soeborg; Søndergaard, Anne; Greve, Aja; Gantriis, Ditte; Jepsen, Jens R M; Mors, Ole; Plessen, Kerstin J; Nordentoft, Merete; Thorup, Anne A E.

In: European Child & Adolescent Psychiatry, Vol. 29, 2020, p. 849–860.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ellersgaard, D, Gregersen, M, Ranning, A, Haspang, TM, Christiani, C, Hemager, N, Burton, BK, Spang, KS, Søndergaard, A, Greve, A, Gantriis, D, Jepsen, JRM, Mors, O, Plessen, KJ, Nordentoft, M & Thorup, AAE 2020, 'Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study', European Child & Adolescent Psychiatry, vol. 29, pp. 849–860. https://doi.org/10.1007/s00787-019-01397-3

APA

Ellersgaard, D., Gregersen, M., Ranning, A., Haspang, T. M., Christiani, C., Hemager, N., Burton, B. K., Spang, K. S., Søndergaard, A., Greve, A., Gantriis, D., Jepsen, J. R. M., Mors, O., Plessen, K. J., Nordentoft, M., & Thorup, A. A. E. (2020). Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study. European Child & Adolescent Psychiatry, 29, 849–860. https://doi.org/10.1007/s00787-019-01397-3

Vancouver

Ellersgaard D, Gregersen M, Ranning A, Haspang TM, Christiani C, Hemager N et al. Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study. European Child & Adolescent Psychiatry. 2020;29:849–860. https://doi.org/10.1007/s00787-019-01397-3

Author

Ellersgaard, Ditte ; Gregersen, Maja ; Ranning, Anne ; Haspang, Thilde M ; Christiani, Camilla ; Hemager, Nicoline ; Burton, Birgitte Klee ; Spang, Katrine Soeborg ; Søndergaard, Anne ; Greve, Aja ; Gantriis, Ditte ; Jepsen, Jens R M ; Mors, Ole ; Plessen, Kerstin J ; Nordentoft, Merete ; Thorup, Anne A E. / Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder : the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study. In: European Child & Adolescent Psychiatry. 2020 ; Vol. 29. pp. 849–860.

Bibtex

@article{cf07a18346194407b860399ed5131339,
title = "Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study",
abstract = "It is well established that children with familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) have a higher risk of developing mental disorders, however, little is known of to what degree the genetic and environmental vulnerabilities affect the quality of life and self-esteem of these children. We aimed to compare the quality of life and self-esteem between children with FHR-SZ or FHR-BP and controls. We used Danish nationwide registers to retrieve a cohort of 522 7-year-old children with FHR-SZ or FHR-BP and controls. Quality of life was assessed with the 'Health-related Quality of Life Screening Instrument', KIDSCREEN-27, and the scale 'Social Acceptance (Bullying)' from the KIDSCREEN-52. Self-esteem was assessed with the self-report scale 'I think I am'. Assessors were blind to familial risk status of the children. Children with FHR-SZ displayed lower levels of the general quality of life, as well as lower scores on the 'Psychological Well-being' scale and the 'School Environment' scale of the KIDSCREEN-27 compared with controls. Both children with FHR-SZ and FHR-BP reported more bullying victimization compared with controls. Children with FHR-SZ reported lower self-esteem on the total scale of 'I think I am', as well as on the 'Skills and talents', the 'Psychological well-being', and the 'Relationships with others' subscales compared with controls. The findings of lower quality of life and self-esteem in children with FHR-SZ together with more bullying victimization in both familial high-risk groups call for studies on low risk, early intervention strategies towards this group of vulnerable children.",
author = "Ditte Ellersgaard and Maja Gregersen and Anne Ranning and Haspang, {Thilde M} and Camilla Christiani and Nicoline Hemager and Burton, {Birgitte Klee} and Spang, {Katrine Soeborg} and Anne S{\o}ndergaard and Aja Greve and Ditte Gantriis and Jepsen, {Jens R M} and Ole Mors and Plessen, {Kerstin J} and Merete Nordentoft and Thorup, {Anne A E}",
year = "2020",
doi = "10.1007/s00787-019-01397-3",
language = "English",
volume = "29",
pages = "849–860",
journal = "European Child and Adolescent Psychiatry, Supplement",
issn = "1433-5719",
publisher = "Springer Medizin",

}

RIS

TY - JOUR

T1 - Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder

T2 - the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study

AU - Ellersgaard, Ditte

AU - Gregersen, Maja

AU - Ranning, Anne

AU - Haspang, Thilde M

AU - Christiani, Camilla

AU - Hemager, Nicoline

AU - Burton, Birgitte Klee

AU - Spang, Katrine Soeborg

AU - Søndergaard, Anne

AU - Greve, Aja

AU - Gantriis, Ditte

AU - Jepsen, Jens R M

AU - Mors, Ole

AU - Plessen, Kerstin J

AU - Nordentoft, Merete

AU - Thorup, Anne A E

PY - 2020

Y1 - 2020

N2 - It is well established that children with familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) have a higher risk of developing mental disorders, however, little is known of to what degree the genetic and environmental vulnerabilities affect the quality of life and self-esteem of these children. We aimed to compare the quality of life and self-esteem between children with FHR-SZ or FHR-BP and controls. We used Danish nationwide registers to retrieve a cohort of 522 7-year-old children with FHR-SZ or FHR-BP and controls. Quality of life was assessed with the 'Health-related Quality of Life Screening Instrument', KIDSCREEN-27, and the scale 'Social Acceptance (Bullying)' from the KIDSCREEN-52. Self-esteem was assessed with the self-report scale 'I think I am'. Assessors were blind to familial risk status of the children. Children with FHR-SZ displayed lower levels of the general quality of life, as well as lower scores on the 'Psychological Well-being' scale and the 'School Environment' scale of the KIDSCREEN-27 compared with controls. Both children with FHR-SZ and FHR-BP reported more bullying victimization compared with controls. Children with FHR-SZ reported lower self-esteem on the total scale of 'I think I am', as well as on the 'Skills and talents', the 'Psychological well-being', and the 'Relationships with others' subscales compared with controls. The findings of lower quality of life and self-esteem in children with FHR-SZ together with more bullying victimization in both familial high-risk groups call for studies on low risk, early intervention strategies towards this group of vulnerable children.

AB - It is well established that children with familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) have a higher risk of developing mental disorders, however, little is known of to what degree the genetic and environmental vulnerabilities affect the quality of life and self-esteem of these children. We aimed to compare the quality of life and self-esteem between children with FHR-SZ or FHR-BP and controls. We used Danish nationwide registers to retrieve a cohort of 522 7-year-old children with FHR-SZ or FHR-BP and controls. Quality of life was assessed with the 'Health-related Quality of Life Screening Instrument', KIDSCREEN-27, and the scale 'Social Acceptance (Bullying)' from the KIDSCREEN-52. Self-esteem was assessed with the self-report scale 'I think I am'. Assessors were blind to familial risk status of the children. Children with FHR-SZ displayed lower levels of the general quality of life, as well as lower scores on the 'Psychological Well-being' scale and the 'School Environment' scale of the KIDSCREEN-27 compared with controls. Both children with FHR-SZ and FHR-BP reported more bullying victimization compared with controls. Children with FHR-SZ reported lower self-esteem on the total scale of 'I think I am', as well as on the 'Skills and talents', the 'Psychological well-being', and the 'Relationships with others' subscales compared with controls. The findings of lower quality of life and self-esteem in children with FHR-SZ together with more bullying victimization in both familial high-risk groups call for studies on low risk, early intervention strategies towards this group of vulnerable children.

U2 - 10.1007/s00787-019-01397-3

DO - 10.1007/s00787-019-01397-3

M3 - Journal article

C2 - 31494772

VL - 29

SP - 849

EP - 860

JO - European Child and Adolescent Psychiatry, Supplement

JF - European Child and Adolescent Psychiatry, Supplement

SN - 1433-5719

ER -

ID: 237105289