Plasma volume changes during hypoglycaemia: the effect of arterial blood sampling
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Plasma volume changes during hypoglycaemia: the effect of arterial blood sampling. / Hilsted, J; Bendtsen, F; Christensen, N J; Henriksen, Jens Henrik Sahl.
In: Scandinavian Journal of Clinical & Laboratory Investigation, Vol. 50, No. 7, 1990, p. 797-800.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Plasma volume changes during hypoglycaemia: the effect of arterial blood sampling
AU - Hilsted, J
AU - Bendtsen, F
AU - Christensen, N J
AU - Henriksen, Jens Henrik Sahl
N1 - Keywords: Adult; Arteries; Blood Chemical Analysis; Blood Volume; Epinephrine; Hematocrit; Hemodynamics; Humans; Hypoglycemia; Male; Norepinephrine; Veins
PY - 1990
Y1 - 1990
N2 - To investigate whether previously reported changes in venous blood volume and composition induced by acute hypoglycaemia in humans are representative for the entire body we measured erythrocyte 51Cr content, haematocrit, plasma volume, intravascular albumin content and transcapillary escape rate of albumin in arterial and venous blood in seven healthy subjects before and during insulin-induced hypoglycaemia. In both vascular sites blood 51Cr content and the haematocrit increased, plasma volume and intravascular albumin content decreased and the transcapillary escape rate of albumin increased during hypoglycaemia. The magnitude of the changes in arterial and venous blood were not significantly different. These results indicate that the above changes in blood volume and composition are whole-body phenomena: furthermore, the major part of the changes are likely to occur in tissues other than upper extremity muscles.
AB - To investigate whether previously reported changes in venous blood volume and composition induced by acute hypoglycaemia in humans are representative for the entire body we measured erythrocyte 51Cr content, haematocrit, plasma volume, intravascular albumin content and transcapillary escape rate of albumin in arterial and venous blood in seven healthy subjects before and during insulin-induced hypoglycaemia. In both vascular sites blood 51Cr content and the haematocrit increased, plasma volume and intravascular albumin content decreased and the transcapillary escape rate of albumin increased during hypoglycaemia. The magnitude of the changes in arterial and venous blood were not significantly different. These results indicate that the above changes in blood volume and composition are whole-body phenomena: furthermore, the major part of the changes are likely to occur in tissues other than upper extremity muscles.
M3 - Journal article
C2 - 2293342
VL - 50
SP - 797
EP - 800
JO - Scandinavian Journal of Clinical & Laboratory Investigation
JF - Scandinavian Journal of Clinical & Laboratory Investigation
SN - 0036-5513
IS - 7
ER -
ID: 18690219