Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11. / Søndergaard, Anne; Wilms, Martin; Gregersen, Maja; Brandt, Julie Marie; Krantz, Mette Falkenberg; Rohd, Sinnika Birkehøj; Johnsen, Line Korsgaard; Hemager, Nicoline; Hjorthøj, Carsten; Ohland, Jessica; Andreassen, Anna Krogh; Knudsen, Christina Bruun; Veddum, Lotte; Greve, Aja; Bliksted, Vibeke; Mors, Ole; Krustrup, Peter; Thorsteinsson, Troels; Schmidt-Andersen, Peter; Kjærgaard, Morten; Lykkegaard, Kasper; Thorup, Anne Amalie Elgaard; Nordentoft, Merete.

In: Schizophrenia Bulletin Open, Vol. 3, No. 1, sgab055, 2022.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Søndergaard, A, Wilms, M, Gregersen, M, Brandt, JM, Krantz, MF, Rohd, SB, Johnsen, LK, Hemager, N, Hjorthøj, C, Ohland, J, Andreassen, AK, Knudsen, CB, Veddum, L, Greve, A, Bliksted, V, Mors, O, Krustrup, P, Thorsteinsson, T, Schmidt-Andersen, P, Kjærgaard, M, Lykkegaard, K, Thorup, AAE & Nordentoft, M 2022, 'Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11', Schizophrenia Bulletin Open, vol. 3, no. 1, sgab055. https://doi.org/10.1093/schizbullopen/sgab055

APA

Søndergaard, A., Wilms, M., Gregersen, M., Brandt, J. M., Krantz, M. F., Rohd, S. B., Johnsen, L. K., Hemager, N., Hjorthøj, C., Ohland, J., Andreassen, A. K., Knudsen, C. B., Veddum, L., Greve, A., Bliksted, V., Mors, O., Krustrup, P., Thorsteinsson, T., Schmidt-Andersen, P., ... Nordentoft, M. (2022). Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11. Schizophrenia Bulletin Open, 3(1), [sgab055]. https://doi.org/10.1093/schizbullopen/sgab055

Vancouver

Søndergaard A, Wilms M, Gregersen M, Brandt JM, Krantz MF, Rohd SB et al. Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11. Schizophrenia Bulletin Open. 2022;3(1). sgab055. https://doi.org/10.1093/schizbullopen/sgab055

Author

Søndergaard, Anne ; Wilms, Martin ; Gregersen, Maja ; Brandt, Julie Marie ; Krantz, Mette Falkenberg ; Rohd, Sinnika Birkehøj ; Johnsen, Line Korsgaard ; Hemager, Nicoline ; Hjorthøj, Carsten ; Ohland, Jessica ; Andreassen, Anna Krogh ; Knudsen, Christina Bruun ; Veddum, Lotte ; Greve, Aja ; Bliksted, Vibeke ; Mors, Ole ; Krustrup, Peter ; Thorsteinsson, Troels ; Schmidt-Andersen, Peter ; Kjærgaard, Morten ; Lykkegaard, Kasper ; Thorup, Anne Amalie Elgaard ; Nordentoft, Merete. / Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11. In: Schizophrenia Bulletin Open. 2022 ; Vol. 3, No. 1.

Bibtex

@article{3df1452a241e403b8ea18e774488f2fb,

title = "Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11",

abstract = "Objective: People with schizophrenia and bipolar disorder are at increased risk of having comorbid somatic illness. This is partly due to lack of physical activity, which may originate from childhood. Sleep disturbances are associated with schizophrenia and bipolar disorder. We aimed to assess physical activity and sleep in children at familial high risk of schizophrenia or bipolar disorder and population-based controls. Methods: This study is part of The Danish High Risk and Resilience Study - VIA 11. Children aged 11 born to parents with schizophrenia (FHR-SZ) (N = 133), bipolar disorder (FHR-BP) (N = 84), or controls (C) (N = 150) were assessed by accelerometry for an average of 6.9 days. Results: High-intensity physical activity was significantly lower in children at FHR-SZ and FHR-BP compared to controls, (mean hours per day for FHR-SZ: 0.29, SD 0.19, for FHR-BP: 0.27, SD 0.24, and for controls 0.38, SD 0.22, P = <.001). Sleep did not differ between the groups. Conclusion: Children at FHR-SZ or FHR-BP had less physical activity compared to controls. Our study highlights a research area that reveals a hitherto unexplored disadvantage of being born to parents with schizophrenia or bipolar disorder. Further research is needed to enhance better understanding of causal pathways and consequences of reduced physical activity in children with FHR-SZ and FHR-BP. ",

keywords = "Bipolar disorder, Children, High risk, Physical activity, Schizoprenia, Sleep",

author = "Anne S{\o}ndergaard and Martin Wilms and Maja Gregersen and Brandt, {Julie Marie} and Krantz, {Mette Falkenberg} and Rohd, {Sinnika Birkeh{\o}j} and Johnsen, {Line Korsgaard} and Nicoline Hemager and Carsten Hjorth{\o}j and Jessica Ohland and Andreassen, {Anna Krogh} and Knudsen, {Christina Bruun} and Lotte Veddum and Aja Greve and Vibeke Bliksted and Ole Mors and Peter Krustrup and Troels Thorsteinsson and Peter Schmidt-Andersen and Morten Kj{\ae}rgaard and Kasper Lykkegaard and Thorup, {Anne Amalie Elgaard} and Merete Nordentoft",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s) 2021. Published by Oxford University Press on behalf of the University of Maryland's school of medicine, Maryland Psychiatric Research Center.",

year = "2022",

doi = "10.1093/schizbullopen/sgab055",

language = "English",

volume = "3",

journal = "Schizophrenia Bulletin Open",

issn = "2632-7899",

publisher = "Oxford University Press",

number = "1",

}

RIS

TY - JOUR

T1 - Physical activity and sleep in 11-year old children with a familial high risk of schizophrenia or bipolar disorder. The Danish High Risk and Resilience Study - VIA 11

AU - Søndergaard, Anne

AU - Wilms, Martin

AU - Gregersen, Maja

AU - Brandt, Julie Marie

AU - Krantz, Mette Falkenberg

AU - Rohd, Sinnika Birkehøj

AU - Johnsen, Line Korsgaard

AU - Hemager, Nicoline

AU - Hjorthøj, Carsten

AU - Ohland, Jessica

AU - Andreassen, Anna Krogh

AU - Knudsen, Christina Bruun

AU - Veddum, Lotte

AU - Greve, Aja

AU - Bliksted, Vibeke

AU - Mors, Ole

AU - Krustrup, Peter

AU - Thorsteinsson, Troels

AU - Schmidt-Andersen, Peter

AU - Kjærgaard, Morten

AU - Lykkegaard, Kasper

AU - Thorup, Anne Amalie Elgaard

AU - Nordentoft, Merete

PY - 2022

Y1 - 2022

N2 - Objective: People with schizophrenia and bipolar disorder are at increased risk of having comorbid somatic illness. This is partly due to lack of physical activity, which may originate from childhood. Sleep disturbances are associated with schizophrenia and bipolar disorder. We aimed to assess physical activity and sleep in children at familial high risk of schizophrenia or bipolar disorder and population-based controls. Methods: This study is part of The Danish High Risk and Resilience Study - VIA 11. Children aged 11 born to parents with schizophrenia (FHR-SZ) (N = 133), bipolar disorder (FHR-BP) (N = 84), or controls (C) (N = 150) were assessed by accelerometry for an average of 6.9 days. Results: High-intensity physical activity was significantly lower in children at FHR-SZ and FHR-BP compared to controls, (mean hours per day for FHR-SZ: 0.29, SD 0.19, for FHR-BP: 0.27, SD 0.24, and for controls 0.38, SD 0.22, P = <.001). Sleep did not differ between the groups. Conclusion: Children at FHR-SZ or FHR-BP had less physical activity compared to controls. Our study highlights a research area that reveals a hitherto unexplored disadvantage of being born to parents with schizophrenia or bipolar disorder. Further research is needed to enhance better understanding of causal pathways and consequences of reduced physical activity in children with FHR-SZ and FHR-BP.

AB - Objective: People with schizophrenia and bipolar disorder are at increased risk of having comorbid somatic illness. This is partly due to lack of physical activity, which may originate from childhood. Sleep disturbances are associated with schizophrenia and bipolar disorder. We aimed to assess physical activity and sleep in children at familial high risk of schizophrenia or bipolar disorder and population-based controls. Methods: This study is part of The Danish High Risk and Resilience Study - VIA 11. Children aged 11 born to parents with schizophrenia (FHR-SZ) (N = 133), bipolar disorder (FHR-BP) (N = 84), or controls (C) (N = 150) were assessed by accelerometry for an average of 6.9 days. Results: High-intensity physical activity was significantly lower in children at FHR-SZ and FHR-BP compared to controls, (mean hours per day for FHR-SZ: 0.29, SD 0.19, for FHR-BP: 0.27, SD 0.24, and for controls 0.38, SD 0.22, P = <.001). Sleep did not differ between the groups. Conclusion: Children at FHR-SZ or FHR-BP had less physical activity compared to controls. Our study highlights a research area that reveals a hitherto unexplored disadvantage of being born to parents with schizophrenia or bipolar disorder. Further research is needed to enhance better understanding of causal pathways and consequences of reduced physical activity in children with FHR-SZ and FHR-BP.

KW - Bipolar disorder

KW - Children

KW - High risk

KW - Physical activity

KW - Schizoprenia

KW - Sleep

U2 - 10.1093/schizbullopen/sgab055

DO - 10.1093/schizbullopen/sgab055

M3 - Journal article

AN - SCOPUS:85130809643

VL - 3

JO - Schizophrenia Bulletin Open

JF - Schizophrenia Bulletin Open

SN - 2632-7899

IS - 1

M1 - sgab055

ER -

ID: 308890553

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