Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation

Research output: Contribution to journal › Journal article › Research › peer-review

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Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation. / Zeller-Plumhoff, Berit; Akkineni, Ashwini Rahul; Helmholz, Heike; Orlov, Dmytro; Mosshammer, Maria; Kuehl, Michael; Willumeit-Roemer, Regine; Gelinsky, Michael.

In: npj Materials Degradation, Vol. 6, 95, 2022.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Zeller-Plumhoff, B, Akkineni, AR, Helmholz, H, Orlov, D, Mosshammer, M, Kuehl, M, Willumeit-Roemer, R & Gelinsky, M 2022, 'Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation', npj Materials Degradation, vol. 6, 95. https://doi.org/10.1038/s41529-022-00302-9

APA

Zeller-Plumhoff, B., Akkineni, A. R., Helmholz, H., Orlov, D., Mosshammer, M., Kuehl, M., Willumeit-Roemer, R., & Gelinsky, M. (2022). Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation. npj Materials Degradation, 6, [95]. https://doi.org/10.1038/s41529-022-00302-9

Vancouver

Zeller-Plumhoff B, Akkineni AR, Helmholz H, Orlov D, Mosshammer M, Kuehl M et al. Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation. npj Materials Degradation. 2022;6. 95. https://doi.org/10.1038/s41529-022-00302-9

Author

Zeller-Plumhoff, Berit ; Akkineni, Ashwini Rahul ; Helmholz, Heike ; Orlov, Dmytro ; Mosshammer, Maria ; Kuehl, Michael ; Willumeit-Roemer, Regine ; Gelinsky, Michael. / Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation. In: npj Materials Degradation. 2022 ; Vol. 6.

Bibtex

@article{a7e16c7c2e6c4e618e9800cad7df7f58,
title = "Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation",
abstract = "Magnesium (Mg) alloys are becoming increasingly important in the biomedical field as temporary bone implants. However, the biodegradation process of Mg alloys is highly complex and recent findings suggest that oxygen (O-2) consumption is non-negligible. In this study, we give experimental proof of O-2 consumption during Mg degradation under physiological conditions. Specifically, we study pure Mg, Mg-6 wt%Ag and Mg-5 wt%Gd in Hanks' balanced salt solution and Dulbecco's modified Eagle's medium. We show that O-2 consumption and hydrogen evolution are inversely correlated and that O-2 concentrations remain below 7.5% in certain cases, which could have significant implications for bone healing.",
keywords = "PHYSIOLOGICAL CONDITIONS, PURE MAGNESIUM, DEGRADATION, IMAGE, LAYER, MG",
author = "Berit Zeller-Plumhoff and Akkineni, {Ashwini Rahul} and Heike Helmholz and Dmytro Orlov and Maria Mosshammer and Michael Kuehl and Regine Willumeit-Roemer and Michael Gelinsky",
year = "2022",
doi = "10.1038/s41529-022-00302-9",
language = "English",
volume = "6",
journal = "npj Materials Degradation",
issn = "2397-2106",
publisher = "Nature Publishing Group",

}

RIS

TY - JOUR

T1 - Oxygen-sensitive nanoparticles reveal the spatiotemporal dynamics of oxygen reduction during magnesium implant biodegradation

AU - Zeller-Plumhoff, Berit

AU - Akkineni, Ashwini Rahul

AU - Helmholz, Heike

AU - Orlov, Dmytro

AU - Mosshammer, Maria

AU - Kuehl, Michael

AU - Willumeit-Roemer, Regine

AU - Gelinsky, Michael

PY - 2022

Y1 - 2022

N2 - Magnesium (Mg) alloys are becoming increasingly important in the biomedical field as temporary bone implants. However, the biodegradation process of Mg alloys is highly complex and recent findings suggest that oxygen (O-2) consumption is non-negligible. In this study, we give experimental proof of O-2 consumption during Mg degradation under physiological conditions. Specifically, we study pure Mg, Mg-6 wt%Ag and Mg-5 wt%Gd in Hanks' balanced salt solution and Dulbecco's modified Eagle's medium. We show that O-2 consumption and hydrogen evolution are inversely correlated and that O-2 concentrations remain below 7.5% in certain cases, which could have significant implications for bone healing.

AB - Magnesium (Mg) alloys are becoming increasingly important in the biomedical field as temporary bone implants. However, the biodegradation process of Mg alloys is highly complex and recent findings suggest that oxygen (O-2) consumption is non-negligible. In this study, we give experimental proof of O-2 consumption during Mg degradation under physiological conditions. Specifically, we study pure Mg, Mg-6 wt%Ag and Mg-5 wt%Gd in Hanks' balanced salt solution and Dulbecco's modified Eagle's medium. We show that O-2 consumption and hydrogen evolution are inversely correlated and that O-2 concentrations remain below 7.5% in certain cases, which could have significant implications for bone healing.

KW - PHYSIOLOGICAL CONDITIONS

KW - PURE MAGNESIUM

KW - DEGRADATION

KW - IMAGE

KW - LAYER

KW - MG

U2 - 10.1038/s41529-022-00302-9

DO - 10.1038/s41529-022-00302-9

M3 - Journal article

VL - 6

JO - npj Materials Degradation

JF - npj Materials Degradation

SN - 2397-2106

M1 - 95

ER -

ID: 329202734