One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: the role of calorie restriction and exercise
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Background & aims: Fasting and postprandial hypertriacylglycerolemia are important cardiovascular risk factors in women. We sought to examine the effects of acute (1 day), moderate (∼ 2 MJ) energy deficit induced by calorie restriction, exercise, or combination of both on fasting and postprandial triacylglycerol (TAG) metabolism in women.
Methods: Six healthy premenopausal women performed four oral fat tolerance tests in the morning after a day of a) rest (control), b) calorie restriction (∼ 2 MJ), c) exercise (net deficit of ∼ 2 MJ) and d) calorie restriction-plus-exercise (total energy deficit of ∼ 2 MJ).
Results: All energy deficit trials significantly reduced fasting and postprandial total plasma TAG concentrations by 15-23% and 12-23%, respectively, and triacylglycerol-rich lipoprotein TAG concentrations by 37-43% and 25-39%, respectively, compared with the control condition (P < 0.05). Postprandial, but not fasting, total TAG concentrations were approximately 12% lower after exercise compared with diet-induced energy deficit (P = 0.05).
Conclusions: Acute, moderate energy deficit independently of its origin (i.e. diet or exercise or combination of both) reduces fasting and postprandial triacylglycerolemia in women. Exercise elicits a somewhat greater effect than calorie restriction in the postprandial state. The acute effect of diet and exercise should be taken into account when studying the long-term effects of weight loss and exercise training on TAG metabolism.
Original language | English |
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Journal | Clinical Nutrition |
Volume | 29 |
Issue number | 4 |
Pages (from-to) | 459-463 |
Number of pages | 5 |
ISSN | 0261-5614 |
DOIs | |
Publication status | Published - 2010 |
Externally published | Yes |
Bibliographical note
Copyright 2009 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
- Adult, Caloric Restriction/adverse effects, Cardiovascular Diseases/epidemiology, Combined Modality Therapy, Cross-Over Studies, Diet, Reducing/adverse effects, Exercise/physiology, Fasting, Female, Humans, Hypertriglyceridemia/blood, Lipoproteins/blood, Motor Activity/physiology, Physical Endurance/physiology, Postprandial Period, Premenopause, Risk Factors, Triglycerides/blood, Young Adult
Research areas
ID: 290670500