NGMSElect™ and Investigator® Argus X-12 analysis in population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey
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NGMSElect™ and Investigator® Argus X-12 analysis in population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey. / Poulsen, Lena; Tomas Mas, Carmen; Drobnic, Katja; Ivanova, Vilma ; Mogensen, Helle Smidt; Kondili, Aikaterini; Miniati, Penelope ; Bunokiene, Daiva; Jankauskiene, Jurate; Pereira, Vania; Morling, Niels.
In: Forensic Science International: Genetics, Vol. 22, 05.2016, p. 110-112.Research output: Contribution to journal › Letter › Research › peer-review
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TY - JOUR
T1 - NGMSElect™ and Investigator® Argus X-12 analysis in population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey
AU - Poulsen, Lena
AU - Tomas Mas, Carmen
AU - Drobnic, Katja
AU - Ivanova, Vilma
AU - Mogensen, Helle Smidt
AU - Kondili, Aikaterini
AU - Miniati, Penelope
AU - Bunokiene, Daiva
AU - Jankauskiene, Jurate
AU - Pereira, Vania
AU - Morling, Niels
PY - 2016/5
Y1 - 2016/5
N2 - The analysis of STRs is the main tool when studying genetic diversity in populations or when addressing individual identification in forensic casework. Population data are needed to establish reference databases that can be used in the forensic context. To that end, this work investigated five population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey. Individuals were typed for 16 autosomal STRs and 12 X-chromosomal STRs using the NGMSElect™ and Investigator® Argus X-12 kits, respectively. The aim of the study was to characterize the diversity of both STR kits in these population samples and to expand our forensic database.The results showed that all markers were polymorphic in the five populations studied. No haplotype was shared between the males analysed for X-STRs. No statistically significant deviations from Hardy–Weinberg equilibrium were observed for any of the genetic markers included in both the kits. Pairwise LD was only detected in X-STRs between markers located in the same linkage group. Power of discrimination values for males and females and the probability of exclusion in duos and trios were high for the populations in this study.
AB - The analysis of STRs is the main tool when studying genetic diversity in populations or when addressing individual identification in forensic casework. Population data are needed to establish reference databases that can be used in the forensic context. To that end, this work investigated five population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey. Individuals were typed for 16 autosomal STRs and 12 X-chromosomal STRs using the NGMSElect™ and Investigator® Argus X-12 kits, respectively. The aim of the study was to characterize the diversity of both STR kits in these population samples and to expand our forensic database.The results showed that all markers were polymorphic in the five populations studied. No haplotype was shared between the males analysed for X-STRs. No statistically significant deviations from Hardy–Weinberg equilibrium were observed for any of the genetic markers included in both the kits. Pairwise LD was only detected in X-STRs between markers located in the same linkage group. Power of discrimination values for males and females and the probability of exclusion in duos and trios were high for the populations in this study.
U2 - 10.1016/j.fsigen.2016.02.004
DO - 10.1016/j.fsigen.2016.02.004
M3 - Letter
C2 - 26894835
VL - 22
SP - 110
EP - 112
JO - Forensic Science International: Genetics
JF - Forensic Science International: Genetics
SN - 1872-4973
ER -
ID: 155547818