Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Molecular Typing of Treponema pallidum in Denmark : A Nationwide Study of Syphilis. / Salado-Rasmussen, Kirsten; Cowan, Susan; Gerstoft, Jan; Larsen, Helle Kiellberg; Hoffmann, Steen; Knudsen, Troels Bygum; Katzenstein, Terese Lea; Jensen, Jørgen Skov.

In: Acta Dermatovenereologica, Vol. 96, 2016, p. 202-206.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Salado-Rasmussen, K, Cowan, S, Gerstoft, J, Larsen, HK, Hoffmann, S, Knudsen, TB, Katzenstein, TL & Jensen, JS 2016, 'Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis', Acta Dermatovenereologica, vol. 96, pp. 202-206. https://doi.org/10.2340/00015555-2190

APA

Salado-Rasmussen, K., Cowan, S., Gerstoft, J., Larsen, H. K., Hoffmann, S., Knudsen, T. B., Katzenstein, T. L., & Jensen, J. S. (2016). Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis. Acta Dermatovenereologica, 96, 202-206. https://doi.org/10.2340/00015555-2190

Vancouver

Salado-Rasmussen K, Cowan S, Gerstoft J, Larsen HK, Hoffmann S, Knudsen TB et al. Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis. Acta Dermatovenereologica. 2016;96:202-206. https://doi.org/10.2340/00015555-2190

Author

Salado-Rasmussen, Kirsten ; Cowan, Susan ; Gerstoft, Jan ; Larsen, Helle Kiellberg ; Hoffmann, Steen ; Knudsen, Troels Bygum ; Katzenstein, Terese Lea ; Jensen, Jørgen Skov. / Molecular Typing of Treponema pallidum in Denmark : A Nationwide Study of Syphilis. In: Acta Dermatovenereologica. 2016 ; Vol. 96. pp. 202-206.

Bibtex

@article{d152e1cdff6f46afb8b534bb4b0c7825,
title = "Molecular Typing of Treponema pallidum in Denmark: A Nationwide Study of Syphilis",
abstract = "The aim of this nationwide study is to determine the strain type diversity among patients diagnosed with syphilis by PCR during a 4-year period in Denmark. Epidemiological data, including HIV status, for all patients were obtained from the Danish national syphilis registration system. Molecular strain typing was based on characterization of 3 variable treponemal genes, arp, tpr and tp0548. A total of 278 specimens from 269 patients were included. Among the fully typeable specimens (n = 197), 22 strain types were identified, with 1 type, 14d/g, accounting for 54%. The majority (93%) of the patients reported acquiring syphilis in Denmark. Among patients with concurrent HIV, 9 full strain types were identified and no difference in strain type was found by HIV status (p = 0.197). In conclusion, the majority of patients were infected in Denmark and the HIV-infected syphilis patients were diagnosed with a wide spectrum of different strain types of Treponema pallidum.",
author = "Kirsten Salado-Rasmussen and Susan Cowan and Jan Gerstoft and Larsen, {Helle Kiellberg} and Steen Hoffmann and Knudsen, {Troels Bygum} and Katzenstein, {Terese Lea} and Jensen, {J{\o}rgen Skov}",
year = "2016",
doi = "10.2340/00015555-2190",
language = "English",
volume = "96",
pages = "202--206",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato - Venereologica",

}

RIS

TY - JOUR

T1 - Molecular Typing of Treponema pallidum in Denmark

T2 - A Nationwide Study of Syphilis

AU - Salado-Rasmussen, Kirsten

AU - Cowan, Susan

AU - Gerstoft, Jan

AU - Larsen, Helle Kiellberg

AU - Hoffmann, Steen

AU - Knudsen, Troels Bygum

AU - Katzenstein, Terese Lea

AU - Jensen, Jørgen Skov

PY - 2016

Y1 - 2016

N2 - The aim of this nationwide study is to determine the strain type diversity among patients diagnosed with syphilis by PCR during a 4-year period in Denmark. Epidemiological data, including HIV status, for all patients were obtained from the Danish national syphilis registration system. Molecular strain typing was based on characterization of 3 variable treponemal genes, arp, tpr and tp0548. A total of 278 specimens from 269 patients were included. Among the fully typeable specimens (n = 197), 22 strain types were identified, with 1 type, 14d/g, accounting for 54%. The majority (93%) of the patients reported acquiring syphilis in Denmark. Among patients with concurrent HIV, 9 full strain types were identified and no difference in strain type was found by HIV status (p = 0.197). In conclusion, the majority of patients were infected in Denmark and the HIV-infected syphilis patients were diagnosed with a wide spectrum of different strain types of Treponema pallidum.

AB - The aim of this nationwide study is to determine the strain type diversity among patients diagnosed with syphilis by PCR during a 4-year period in Denmark. Epidemiological data, including HIV status, for all patients were obtained from the Danish national syphilis registration system. Molecular strain typing was based on characterization of 3 variable treponemal genes, arp, tpr and tp0548. A total of 278 specimens from 269 patients were included. Among the fully typeable specimens (n = 197), 22 strain types were identified, with 1 type, 14d/g, accounting for 54%. The majority (93%) of the patients reported acquiring syphilis in Denmark. Among patients with concurrent HIV, 9 full strain types were identified and no difference in strain type was found by HIV status (p = 0.197). In conclusion, the majority of patients were infected in Denmark and the HIV-infected syphilis patients were diagnosed with a wide spectrum of different strain types of Treponema pallidum.

U2 - 10.2340/00015555-2190

DO - 10.2340/00015555-2190

M3 - Journal article

C2 - 26122912

VL - 96

SP - 202

EP - 206

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

ER -

ID: 161420321