miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis. / Wang, Li; Gu, Xiaolu; Xu, Deyang; Wang, Wei; Wang, Hua; Zeng, Minhuan; Chang, Zhaoyang; Huang, Hai; Cui, Xiaofeng.

In: Journal of Experimental Botany. Flowering Newsletter, Vol. 62, No. 2, 2011, p. 761-773.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Wang, L, Gu, X, Xu, D, Wang, W, Wang, H, Zeng, M, Chang, Z, Huang, H & Cui, X 2011, 'miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis', Journal of Experimental Botany. Flowering Newsletter, vol. 62, no. 2, pp. 761-773. https://doi.org/10.1093/jxb/erq307

APA

Wang, L., Gu, X., Xu, D., Wang, W., Wang, H., Zeng, M., Chang, Z., Huang, H., & Cui, X. (2011). miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis. Journal of Experimental Botany. Flowering Newsletter, 62(2), 761-773. https://doi.org/10.1093/jxb/erq307

Vancouver

Wang L, Gu X, Xu D, Wang W, Wang H, Zeng M et al. miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis. Journal of Experimental Botany. Flowering Newsletter. 2011;62(2):761-773. https://doi.org/10.1093/jxb/erq307

Author

Wang, Li ; Gu, Xiaolu ; Xu, Deyang ; Wang, Wei ; Wang, Hua ; Zeng, Minhuan ; Chang, Zhaoyang ; Huang, Hai ; Cui, Xiaofeng. / miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis. In: Journal of Experimental Botany. Flowering Newsletter. 2011 ; Vol. 62, No. 2. pp. 761-773.

Bibtex

@article{a8ef8d03299944d6b226e07d6f82f99a,
title = "miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis",
abstract = "In plants, cell proliferation and polarized cell differentiation along the adaxial-abaxial axis in the primordium is critical for leaf morphogenesis, while the temporal-spatial relationships between these two processes remain largely unexplored. Here, it is reported that microRNA396 (miR396)-targeted Arabidopsis growth-regulating factors (AtGRFs) are required for leaf adaxial-abaxial polarity in Arabidopsis. Reduction of the expression of AtGRF genes by transgenic miR396 overexpression in leaf polarity mutants asymmetric leaves1 (as1) and as2 resulted in plants with enhanced leaf adaxial-abaxial defects, as a consequence of reduced cell proliferation. Moreover, transgenic miR396 overexpression markedly decreased the cell division activity and the expression of cell cycle-related genes, but resulted in an increased percentage of leaf cells with a higher ploidy level, indicating that miR396 negatively regulates cell proliferation by controlling entry into the mitotic cell cycle. miR396 is mainly expressed in the leaf cells arrested for cell division, coinciding with its roles in cell cycle regulation. These results together suggest that cell division activity mediated by miR396-targeted AtGRFs is important for polarized cell differentiation along the adaxial-abaxial axis during leaf morphogenesis in Arabidopsis.",
keywords = "Arabidopsis, Arabidopsis Proteins, Cell Differentiation, Cell Division, Gene Expression Regulation, Developmental, Gene Expression Regulation, Plant, Gene Targeting, MicroRNAs, Plant Leaves, Transcription Factors",
author = "Li Wang and Xiaolu Gu and Deyang Xu and Wei Wang and Hua Wang and Minhuan Zeng and Zhaoyang Chang and Hai Huang and Xiaofeng Cui",
year = "2011",
doi = "10.1093/jxb/erq307",
language = "English",
volume = "62",
pages = "761--773",
journal = "Journal of Experimental Botany. Flowering Newsletter",
issn = "1754-6613",
publisher = "Oxford University Press",
number = "2",

}

RIS

TY - JOUR

T1 - miR396-targeted AtGRF transcription factors are required for coordination of cell division and differentiation during leaf development in Arabidopsis

AU - Wang, Li

AU - Gu, Xiaolu

AU - Xu, Deyang

AU - Wang, Wei

AU - Wang, Hua

AU - Zeng, Minhuan

AU - Chang, Zhaoyang

AU - Huang, Hai

AU - Cui, Xiaofeng

PY - 2011

Y1 - 2011

N2 - In plants, cell proliferation and polarized cell differentiation along the adaxial-abaxial axis in the primordium is critical for leaf morphogenesis, while the temporal-spatial relationships between these two processes remain largely unexplored. Here, it is reported that microRNA396 (miR396)-targeted Arabidopsis growth-regulating factors (AtGRFs) are required for leaf adaxial-abaxial polarity in Arabidopsis. Reduction of the expression of AtGRF genes by transgenic miR396 overexpression in leaf polarity mutants asymmetric leaves1 (as1) and as2 resulted in plants with enhanced leaf adaxial-abaxial defects, as a consequence of reduced cell proliferation. Moreover, transgenic miR396 overexpression markedly decreased the cell division activity and the expression of cell cycle-related genes, but resulted in an increased percentage of leaf cells with a higher ploidy level, indicating that miR396 negatively regulates cell proliferation by controlling entry into the mitotic cell cycle. miR396 is mainly expressed in the leaf cells arrested for cell division, coinciding with its roles in cell cycle regulation. These results together suggest that cell division activity mediated by miR396-targeted AtGRFs is important for polarized cell differentiation along the adaxial-abaxial axis during leaf morphogenesis in Arabidopsis.

AB - In plants, cell proliferation and polarized cell differentiation along the adaxial-abaxial axis in the primordium is critical for leaf morphogenesis, while the temporal-spatial relationships between these two processes remain largely unexplored. Here, it is reported that microRNA396 (miR396)-targeted Arabidopsis growth-regulating factors (AtGRFs) are required for leaf adaxial-abaxial polarity in Arabidopsis. Reduction of the expression of AtGRF genes by transgenic miR396 overexpression in leaf polarity mutants asymmetric leaves1 (as1) and as2 resulted in plants with enhanced leaf adaxial-abaxial defects, as a consequence of reduced cell proliferation. Moreover, transgenic miR396 overexpression markedly decreased the cell division activity and the expression of cell cycle-related genes, but resulted in an increased percentage of leaf cells with a higher ploidy level, indicating that miR396 negatively regulates cell proliferation by controlling entry into the mitotic cell cycle. miR396 is mainly expressed in the leaf cells arrested for cell division, coinciding with its roles in cell cycle regulation. These results together suggest that cell division activity mediated by miR396-targeted AtGRFs is important for polarized cell differentiation along the adaxial-abaxial axis during leaf morphogenesis in Arabidopsis.

KW - Arabidopsis

KW - Arabidopsis Proteins

KW - Cell Differentiation

KW - Cell Division

KW - Gene Expression Regulation, Developmental

KW - Gene Expression Regulation, Plant

KW - Gene Targeting

KW - MicroRNAs

KW - Plant Leaves

KW - Transcription Factors

U2 - 10.1093/jxb/erq307

DO - 10.1093/jxb/erq307

M3 - Journal article

C2 - 21036927

VL - 62

SP - 761

EP - 773

JO - Journal of Experimental Botany. Flowering Newsletter

JF - Journal of Experimental Botany. Flowering Newsletter

SN - 1754-6613

IS - 2

ER -

ID: 146748375