Migraine and structural abnormalities in the brain

Research output: Contribution to journal › Review › Research › peer-review

Standard

Migraine and structural abnormalities in the brain. / Hougaard, Anders; Amin, Faisal Mohammad; Ashina, Messoud.

In: Current Opinion in Neurology, Vol. 27, No. 3, 06.2014, p. 309-314.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Hougaard, A, Amin, FM & Ashina, M 2014, 'Migraine and structural abnormalities in the brain', Current Opinion in Neurology, vol. 27, no. 3, pp. 309-314. https://doi.org/10.1097/WCO.0000000000000086

APA

Hougaard, A., Amin, F. M., & Ashina, M. (2014). Migraine and structural abnormalities in the brain. Current Opinion in Neurology, 27(3), 309-314. https://doi.org/10.1097/WCO.0000000000000086

Vancouver

Hougaard A, Amin FM, Ashina M. Migraine and structural abnormalities in the brain. Current Opinion in Neurology. 2014 Jun;27(3):309-314. https://doi.org/10.1097/WCO.0000000000000086

Author

Hougaard, Anders ; Amin, Faisal Mohammad ; Ashina, Messoud. / Migraine and structural abnormalities in the brain. In: Current Opinion in Neurology. 2014 ; Vol. 27, No. 3. pp. 309-314.

Bibtex

@article{e058796f4c194741bc22010ae2efb2b1,
title = "Migraine and structural abnormalities in the brain",
abstract = "PURPOSE OF REVIEW: The aim is to provide an overview of recent studies of structural brain abnormalities in migraine and to discuss the potential clinical significance of their findings.RECENT FINDINGS: Brain structure continues to be a topic of extensive research in migraine. Despite advances in neuroimaging techniques, it is not yet clear if migraine is associated with grey matter changes. Recent large population-based studies sustain the notion of increased prevalence of white matter abnormalities in migraine, and possibly of silent infarct-like lesions. The clinical relevance of this association is not clear. Structural changes are not related to cognitive decline, but a link to an increased risk of stroke, especially in patients with aura, cannot be ruled out.SUMMARY: Migraine may be a risk factor for structural changes in the brain. It is not yet clear how factors such as migraine sub-type, attack frequency, and sex affects this association. Additional longitudinal studies are needed to address these issues. Brain structure changes in migraine could potentially serve as disease biomarkers or as a mean of identifying sub-groups of patients with specific therapeutic needs and prognoses.",
keywords = "Brain, Brain Infarction, Gray Matter, Humans, Magnetic Resonance Imaging, Migraine Disorders, White Matter",
author = "Anders Hougaard and Amin, {Faisal Mohammad} and Messoud Ashina",
year = "2014",
month = jun,
doi = "10.1097/WCO.0000000000000086",
language = "English",
volume = "27",
pages = "309--314",
journal = "Current Opinion in Neurology",
issn = "1350-7540",
publisher = "Lippincott Williams & Wilkins, Ltd.",
number = "3",

}

RIS

TY - JOUR

T1 - Migraine and structural abnormalities in the brain

AU - Hougaard, Anders

AU - Amin, Faisal Mohammad

AU - Ashina, Messoud

PY - 2014/6

Y1 - 2014/6

N2 - PURPOSE OF REVIEW: The aim is to provide an overview of recent studies of structural brain abnormalities in migraine and to discuss the potential clinical significance of their findings.RECENT FINDINGS: Brain structure continues to be a topic of extensive research in migraine. Despite advances in neuroimaging techniques, it is not yet clear if migraine is associated with grey matter changes. Recent large population-based studies sustain the notion of increased prevalence of white matter abnormalities in migraine, and possibly of silent infarct-like lesions. The clinical relevance of this association is not clear. Structural changes are not related to cognitive decline, but a link to an increased risk of stroke, especially in patients with aura, cannot be ruled out.SUMMARY: Migraine may be a risk factor for structural changes in the brain. It is not yet clear how factors such as migraine sub-type, attack frequency, and sex affects this association. Additional longitudinal studies are needed to address these issues. Brain structure changes in migraine could potentially serve as disease biomarkers or as a mean of identifying sub-groups of patients with specific therapeutic needs and prognoses.

AB - PURPOSE OF REVIEW: The aim is to provide an overview of recent studies of structural brain abnormalities in migraine and to discuss the potential clinical significance of their findings.RECENT FINDINGS: Brain structure continues to be a topic of extensive research in migraine. Despite advances in neuroimaging techniques, it is not yet clear if migraine is associated with grey matter changes. Recent large population-based studies sustain the notion of increased prevalence of white matter abnormalities in migraine, and possibly of silent infarct-like lesions. The clinical relevance of this association is not clear. Structural changes are not related to cognitive decline, but a link to an increased risk of stroke, especially in patients with aura, cannot be ruled out.SUMMARY: Migraine may be a risk factor for structural changes in the brain. It is not yet clear how factors such as migraine sub-type, attack frequency, and sex affects this association. Additional longitudinal studies are needed to address these issues. Brain structure changes in migraine could potentially serve as disease biomarkers or as a mean of identifying sub-groups of patients with specific therapeutic needs and prognoses.

KW - Brain

KW - Brain Infarction

KW - Gray Matter

KW - Humans

KW - Magnetic Resonance Imaging

KW - Migraine Disorders

KW - White Matter

U2 - 10.1097/WCO.0000000000000086

DO - 10.1097/WCO.0000000000000086

M3 - Review

C2 - 24751961

VL - 27

SP - 309

EP - 314

JO - Current Opinion in Neurology

JF - Current Opinion in Neurology

SN - 1350-7540

IS - 3

ER -

ID: 138429991