Light bodies in human pituitary adenomas.

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Light bodies in human pituitary adenomas. / Holck, S; Wewer, U M; Albrechtsen, R.

In: Virchows Archiv, Vol. 411, No. 4, 1987, p. 311-4.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Holck, S, Wewer, UM & Albrechtsen, R 1987, 'Light bodies in human pituitary adenomas.', Virchows Archiv, vol. 411, no. 4, pp. 311-4.

APA

Holck, S., Wewer, U. M., & Albrechtsen, R. (1987). Light bodies in human pituitary adenomas. Virchows Archiv, 411(4), 311-4.

Vancouver

Holck S, Wewer UM, Albrechtsen R. Light bodies in human pituitary adenomas. Virchows Archiv. 1987;411(4):311-4.

Author

Holck, S ; Wewer, U M ; Albrechtsen, R. / Light bodies in human pituitary adenomas. In: Virchows Archiv. 1987 ; Vol. 411, No. 4. pp. 311-4.

Bibtex

@article{c4378dc05c7f11dd8d9f000ea68e967b,
title = "Light bodies in human pituitary adenomas.",
abstract = "Light bodies are large cytoplasmic granules originally described in the gonadotrophic cells of the rat pituitary gland. In order to determine whether similar bodies occur in the human anterior pituitary gland, 89 pituitary adenomas and periadenomatous tissue from 20 cases were examined by transmission electron microscopy. Double membrane bound bodies with filamentous internal structure identical to rodent light bodies were identified in 10 hormone-producing adenomas: 5 PRL, 1 PRL-GH, 2 GH, and 2 ACTH-producing tumours. No light bodies were found in the remaining 79 tumours nor in the pituitary cells in periadenomatous tissue from 20 cases. These results show that some human pituitary adenomas may contain light bodies identical to those seen in gonadotrophs of rat pituitary.",
author = "S Holck and Wewer, {U M} and R Albrechtsen",
note = "Keywords: Adenoma; Adult; Female; Humans; Male; Microscopy, Electron; Organoids; Pituitary Hormones; Pituitary Neoplasms",
year = "1987",
language = "English",
volume = "411",
pages = "311--4",
journal = "Virchows Archiv",
issn = "0945-6317",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Light bodies in human pituitary adenomas.

AU - Holck, S

AU - Wewer, U M

AU - Albrechtsen, R

N1 - Keywords: Adenoma; Adult; Female; Humans; Male; Microscopy, Electron; Organoids; Pituitary Hormones; Pituitary Neoplasms

PY - 1987

Y1 - 1987

N2 - Light bodies are large cytoplasmic granules originally described in the gonadotrophic cells of the rat pituitary gland. In order to determine whether similar bodies occur in the human anterior pituitary gland, 89 pituitary adenomas and periadenomatous tissue from 20 cases were examined by transmission electron microscopy. Double membrane bound bodies with filamentous internal structure identical to rodent light bodies were identified in 10 hormone-producing adenomas: 5 PRL, 1 PRL-GH, 2 GH, and 2 ACTH-producing tumours. No light bodies were found in the remaining 79 tumours nor in the pituitary cells in periadenomatous tissue from 20 cases. These results show that some human pituitary adenomas may contain light bodies identical to those seen in gonadotrophs of rat pituitary.

AB - Light bodies are large cytoplasmic granules originally described in the gonadotrophic cells of the rat pituitary gland. In order to determine whether similar bodies occur in the human anterior pituitary gland, 89 pituitary adenomas and periadenomatous tissue from 20 cases were examined by transmission electron microscopy. Double membrane bound bodies with filamentous internal structure identical to rodent light bodies were identified in 10 hormone-producing adenomas: 5 PRL, 1 PRL-GH, 2 GH, and 2 ACTH-producing tumours. No light bodies were found in the remaining 79 tumours nor in the pituitary cells in periadenomatous tissue from 20 cases. These results show that some human pituitary adenomas may contain light bodies identical to those seen in gonadotrophs of rat pituitary.

M3 - Journal article

C2 - 3114943

VL - 411

SP - 311

EP - 314

JO - Virchows Archiv

JF - Virchows Archiv

SN - 0945-6317

IS - 4

ER -

ID: 5236976