Is a targeted intensive intervention effective for improvements in hypertension control? A randomized controlled trial
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Is a targeted intensive intervention effective for improvements in hypertension control? A randomized controlled trial. / Reuther, Lene Ørskov; Paulsen, Maja Skov; Andersen, Morten; Schultz-Larsen, Peter; Christensen, Hanne Rolighed; Munck, Anders; Larsen, Pia Veldt; Damsgaard, Jens Kristian; Poulsen, Lars; Hansen, Dorte Gilså; Christensen, Bo Allesøe; Søndergaard, Jens Foged; Andersen, Morten; Poulsen, Lars.
In: Family Practice, Vol. 29, No. 6, 2012, p. 626-632.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Is a targeted intensive intervention effective for improvements in hypertension control?
T2 - A randomized controlled trial
AU - Reuther, Lene Ørskov
AU - Paulsen, Maja Skov
AU - Andersen, Morten
AU - Schultz-Larsen, Peter
AU - Christensen, Hanne Rolighed
AU - Munck, Anders
AU - Larsen, Pia Veldt
AU - Damsgaard, Jens Kristian
AU - Poulsen, Lars
AU - Hansen, Dorte Gilså
AU - Christensen, Bo Allesøe
AU - Søndergaard, Jens Foged
AU - Andersen, Morten
AU - Poulsen, Lars
PY - 2012
Y1 - 2012
N2 - BACKGROUND: High blood pressure (BP) is one of the most important risk factors for stroke, and antihypertensive therapy significantly reduces the risk of cardiovascular morbidity and mortality. However, achieving a regulated BP in hypertensive patients is still a challenge. OBJECTIVE: To evaluate the impact of an intervention targeting GPs' management of hypertension. METHODS: A cluster randomized trial comprising 124 practices and 2646 patients with hypertension. In the Capital Region of Denmark, the participating GPs were randomized to an intensive or to a moderately intensive intervention group or to a control group and in Region Zealand and Region of Southern Denmark, practices were randomized into a moderately intensive intervention and to a control group. The main outcome measures were change in proportion of patients with high BP and change in systolic BP (SBP) and diastolic BP (DBP) from the first to the second registration. RESULTS: The proportion of patients with high BP in 2007 was reduced in 2009 by ~9% points. The mean SBP was reduced significantly from 2007 to 2009 by 3.61 mmHg [95% confidence interval (CI): -4.26 to -2.96], and the DBP was reduced significantly by 1.99 mmHg (95% CI: -2.37 to -1.61). There was no additional impact in either of the intervention groups. CONCLUSION: There was no impact of the moderate intervention and no additional impact of the intensive intervention on BP.
AB - BACKGROUND: High blood pressure (BP) is one of the most important risk factors for stroke, and antihypertensive therapy significantly reduces the risk of cardiovascular morbidity and mortality. However, achieving a regulated BP in hypertensive patients is still a challenge. OBJECTIVE: To evaluate the impact of an intervention targeting GPs' management of hypertension. METHODS: A cluster randomized trial comprising 124 practices and 2646 patients with hypertension. In the Capital Region of Denmark, the participating GPs were randomized to an intensive or to a moderately intensive intervention group or to a control group and in Region Zealand and Region of Southern Denmark, practices were randomized into a moderately intensive intervention and to a control group. The main outcome measures were change in proportion of patients with high BP and change in systolic BP (SBP) and diastolic BP (DBP) from the first to the second registration. RESULTS: The proportion of patients with high BP in 2007 was reduced in 2009 by ~9% points. The mean SBP was reduced significantly from 2007 to 2009 by 3.61 mmHg [95% confidence interval (CI): -4.26 to -2.96], and the DBP was reduced significantly by 1.99 mmHg (95% CI: -2.37 to -1.61). There was no additional impact in either of the intervention groups. CONCLUSION: There was no impact of the moderate intervention and no additional impact of the intensive intervention on BP.
U2 - 10.1093/fampra/cms031
DO - 10.1093/fampra/cms031
M3 - Journal article
C2 - 22565110
VL - 29
SP - 626
EP - 632
JO - Family Practice
JF - Family Practice
SN - 0263-2136
IS - 6
ER -
ID: 40190067