Improvement in age-related cognitive functions and life expectancy by ketogenic diets
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Improvement in age-related cognitive functions and life expectancy by ketogenic diets. / Astrup, Arne; Hjorth, Mads Fiil.
In: Nature Reviews Endocrinology, Vol. 13, No. 12, 2017, p. 695-696.Research output: Contribution to journal › Letter › Research › peer-review
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TY - JOUR
T1 - Improvement in age-related cognitive functions and life expectancy by ketogenic diets
AU - Astrup, Arne
AU - Hjorth, Mads Fiil
N1 - CURIS 2017 NEXS 300
PY - 2017
Y1 - 2017
N2 - Rodent studies have indicated that low-carbohydrate diets prevent age-related cognitive decline and extend lifespan due to increased circulating levels of ketone bodies. A possible physiological mechanism for how ketone bodies exert this effect might be by improving central nervous system insulin resistance, which makes this finding interesting with regards to the prevention of cognitive decline and dementia in patients with type 2 diabetes mellitus.
AB - Rodent studies have indicated that low-carbohydrate diets prevent age-related cognitive decline and extend lifespan due to increased circulating levels of ketone bodies. A possible physiological mechanism for how ketone bodies exert this effect might be by improving central nervous system insulin resistance, which makes this finding interesting with regards to the prevention of cognitive decline and dementia in patients with type 2 diabetes mellitus.
KW - Ageing
U2 - 10.1038/nrendo.2017.142
DO - 10.1038/nrendo.2017.142
M3 - Letter
C2 - 29118350
VL - 13
SP - 695
EP - 696
JO - Nature Reviews Endocrinology
JF - Nature Reviews Endocrinology
SN - 1759-5029
IS - 12
ER -
ID: 185507546