High plasma levels of intact and cleaved soluble urokinase receptor reflect immune activation and are independent predictors of mortality in HIV-1-infected patients
Research output: Contribution to journal › Journal article › Research › peer-review
High blood levels of soluble urokinase receptor (suPAR) measured by enzyme-linked immunoassay (ELISA) (bulk measurement of 3-domain and 2-domain suPAR [suPAR(I-III), suPAR(II-III)], and suPAR(I-III) ligand complexes) strongly predict mortality in HIV-1-infected patients. This study investigated plasma levels of suPAR(I-III), suPAR(II-III), and 1-domain suPAR [suPAR(I)] and their predictive value for survival in HIV patients.
| Original language | English |
|---|---|
| Journal | J A I D S |
| Volume | 39 |
| Issue number | 1 |
| Pages (from-to) | 23-31 |
| Number of pages | 9 |
| ISSN | 1525-4135 |
| Publication status | Published - 2005 |
- Adult, Analysis of Variance, Antigens, CD, Biological Markers, Disease Progression, Enzyme-Linked Immunosorbent Assay, Female, HIV Infections, Humans, Leukocyte Count, Lymphocyte Activation, Male, Middle Aged, Multivariate Analysis, RNA, Viral, Receptors, Cell Surface, Receptors, Urokinase Plasminogen Activator, Reference Values, Regression Analysis, Survival Analysis, Viral Load
Research areas
ID: 36143881