High incidence of secondary hypertension in patients referred for renal denervation: the Copenhagen experience
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High incidence of secondary hypertension in patients referred for renal denervation : the Copenhagen experience. / Olsen, Lene Kjær; Kamper, Anne-Lise; Svendsen, Jesper Hastrup; Bang, Lia Evi; Frimodt-Møller, Marie; Kelbæk, Henning; Sander, Mikael; Feldt-Rasmussen, Bo.
In: Blood Pressure, Vol. 23, No. 4, 08.2014, p. 233-239.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - High incidence of secondary hypertension in patients referred for renal denervation
T2 - the Copenhagen experience
AU - Olsen, Lene Kjær
AU - Kamper, Anne-Lise
AU - Svendsen, Jesper Hastrup
AU - Bang, Lia Evi
AU - Frimodt-Møller, Marie
AU - Kelbæk, Henning
AU - Sander, Mikael
AU - Feldt-Rasmussen, Bo
PY - 2014/8
Y1 - 2014/8
N2 - Percutaneous renal denervation is a new treatment option for patients with resistant hypertension and little is known about the eligibility of patients referred. 100 consecutive patients were referred for renal denervation from March 2011 through September 2012. Clinical data were prospectively extracted from letters and documents from referring clinics and from our physical examination. Of the 100 patients included, 68 were men and the mean age was 60 (± 12) years. Office blood pressure was 176 (± 28)/99 (± 19) mmHg and 24-h ambulatory blood pressure 156 (± 20)/88 (± 13) mmHg. The mean number of antihypertensive agents was 4.0 (± 1.6). Nearly four-fifths (82%) of the patients were categorized as having resistant hypertension based on the criteria stated by The American Heart Association's stated criteria. Nine patients declined interest in renal denervation before completing the clinical workup program. Thus, 91 patients were screened, and of those 51 were found to be candidates for renal denervation. Forty patients were not candidates, of which secondary hypertension was the most common cause (n = 10). Only 51% of patients referred for renal denervation were eligible for treatment. The prevalence of secondary hypertension was 10% of the referred population. Secondary hypertension should therefore be considered in the evaluation of candidates for renal denervation.
AB - Percutaneous renal denervation is a new treatment option for patients with resistant hypertension and little is known about the eligibility of patients referred. 100 consecutive patients were referred for renal denervation from March 2011 through September 2012. Clinical data were prospectively extracted from letters and documents from referring clinics and from our physical examination. Of the 100 patients included, 68 were men and the mean age was 60 (± 12) years. Office blood pressure was 176 (± 28)/99 (± 19) mmHg and 24-h ambulatory blood pressure 156 (± 20)/88 (± 13) mmHg. The mean number of antihypertensive agents was 4.0 (± 1.6). Nearly four-fifths (82%) of the patients were categorized as having resistant hypertension based on the criteria stated by The American Heart Association's stated criteria. Nine patients declined interest in renal denervation before completing the clinical workup program. Thus, 91 patients were screened, and of those 51 were found to be candidates for renal denervation. Forty patients were not candidates, of which secondary hypertension was the most common cause (n = 10). Only 51% of patients referred for renal denervation were eligible for treatment. The prevalence of secondary hypertension was 10% of the referred population. Secondary hypertension should therefore be considered in the evaluation of candidates for renal denervation.
KW - Blood Pressure Monitoring, Ambulatory
KW - Denmark
KW - Female
KW - Humans
KW - Hypertension
KW - Kidney
KW - Male
KW - Middle Aged
KW - Prospective Studies
KW - Sympathectomy
U2 - 10.3109/08037051.2013.867655
DO - 10.3109/08037051.2013.867655
M3 - Journal article
C2 - 24437697
VL - 23
SP - 233
EP - 239
JO - Blood Pressure
JF - Blood Pressure
SN - 0803-7051
IS - 4
ER -
ID: 138174806