Health-related quality of life in Iranian patients with multiple sclerosis: a cross-cultural study
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Health-related quality of life in Iranian patients with multiple sclerosis : a cross-cultural study. / Pakpour, Amir H.; Yekaninejad, Mir Saeed; Mohammadi, Nastaran Keshavarz; Molsted, Stig; Zarei, Fatemeh; Patti, Francesco; Harrison, Adrian.
In: Neurologia i Neurochirurgia Polska, Vol. 43, No. 6, 08.01.2010, p. 517-26.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Health-related quality of life in Iranian patients with multiple sclerosis
T2 - a cross-cultural study
AU - Pakpour, Amir H.
AU - Yekaninejad, Mir Saeed
AU - Mohammadi, Nastaran Keshavarz
AU - Molsted, Stig
AU - Zarei, Fatemeh
AU - Patti, Francesco
AU - Harrison, Adrian
PY - 2010/1/8
Y1 - 2010/1/8
N2 - BACKGROUND AND PURPOSE: This study aimed to evaluate aspects of health-related quality of life (HRQoL) of patients with multiple sclerosis (MS) who live in Tehran and to compare data with evaluations of both the general population and MS patients in other countries.MATERIAL AND METHODS: One hundred and forty patients with MS, yet without severe comorbidity, were selected according to convenience sampling in a cross-sectional study. Data were collected by means of the SF-36 questionnaire and Beck Depression Inventory (BDI). The Expanded Disability Status Scale of Kurtzke (EDSS) and Mini Mental State Examination were recorded for all patients.RESULTS: The mean age of the participants was 34.7 years. For all SF-36 scales, MS patients were found to have lower scores, after adjustment for sex and age, compared with the general population. BDI and EDSS scores were significantly and negatively correlated with all of the SF-36 scales. Moreover, the BDI and EDSS were found to be positively correlated with one another (r = 0.415, p < 0.01).CONCLUSIONS: The findings strongly confirm that patients with MS suffer from poor HRQoL. Depression had a strong effect on HRQoL and in order to improve HRQoL in MS patients the prevention and treatment of depression is vital.
AB - BACKGROUND AND PURPOSE: This study aimed to evaluate aspects of health-related quality of life (HRQoL) of patients with multiple sclerosis (MS) who live in Tehran and to compare data with evaluations of both the general population and MS patients in other countries.MATERIAL AND METHODS: One hundred and forty patients with MS, yet without severe comorbidity, were selected according to convenience sampling in a cross-sectional study. Data were collected by means of the SF-36 questionnaire and Beck Depression Inventory (BDI). The Expanded Disability Status Scale of Kurtzke (EDSS) and Mini Mental State Examination were recorded for all patients.RESULTS: The mean age of the participants was 34.7 years. For all SF-36 scales, MS patients were found to have lower scores, after adjustment for sex and age, compared with the general population. BDI and EDSS scores were significantly and negatively correlated with all of the SF-36 scales. Moreover, the BDI and EDSS were found to be positively correlated with one another (r = 0.415, p < 0.01).CONCLUSIONS: The findings strongly confirm that patients with MS suffer from poor HRQoL. Depression had a strong effect on HRQoL and in order to improve HRQoL in MS patients the prevention and treatment of depression is vital.
KW - Activities of Daily Living
KW - Adult
KW - Comorbidity
KW - Cross-Cultural Comparison
KW - Cross-Sectional Studies
KW - Depression
KW - Disability Evaluation
KW - Female
KW - Health Status
KW - Humans
KW - Iran
KW - Male
KW - Middle Aged
KW - Multiple Sclerosis
KW - Quality of Life
KW - Self Concept
KW - Severity of Illness Index
KW - Surveys and Questionnaires
KW - Comparative Study
KW - Journal Article
M3 - Journal article
C2 - 20054754
VL - 43
SP - 517
EP - 526
JO - Neurologia i Neurochirurgia Polska
JF - Neurologia i Neurochirurgia Polska
SN - 0028-3843
IS - 6
ER -
ID: 177291934