Genomet og diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
In terms of their genetic architecture monogenic diabetes and type 2 diabetes represent two extremes. Whereas each subtype of monogenic diabetes is caused by one penetrant, rare mutation in a single gene, the genetic susceptibility to type 2 diabetes can be attributed to many low-penetrant variants across the genome. At present, only 10% of the genetic susceptibility to type 2 diabetes can be explained by the hitherto identified 90 genomic loci. Here we briefly review the genetics of monogenic diabetes and type 2 diabetes and outline future directions of research within this field.
Original language | Danish |
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Article number | V06140337 |
Journal | Ugeskrift for Laeger |
Volume | 176 |
Issue number | 23 |
Pages (from-to) | 2176-2179 |
ISSN | 0041-5782 |
Publication status | Published - 10 Nov 2014 |
Links
- http://ugeskriftet.dk/videnskab/genomet-og-diabetes
Final published version
ID: 148552424