Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho. / Narvestad-Bøttger, Helene; Winther-Larsen, Anne; Haugbølle Bjerre, Jens; Dziegiel, Morten Hanefeld; Hansen, Anne Todsen; Hasle, Henrik.

In: Journal of Pediatric Hematology/Oncology, Vol. 46, No. 1, 01.01.2024, p. E111-E114.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Narvestad-Bøttger, H, Winther-Larsen, A, Haugbølle Bjerre, J, Dziegiel, MH, Hansen, AT & Hasle, H 2024, 'Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho', Journal of Pediatric Hematology/Oncology, vol. 46, no. 1, pp. E111-E114. https://doi.org/10.1097/MPH.0000000000002790

APA

Narvestad-Bøttger, H., Winther-Larsen, A., Haugbølle Bjerre, J., Dziegiel, M. H., Hansen, A. T., & Hasle, H. (2024). Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho. Journal of Pediatric Hematology/Oncology, 46(1), E111-E114. https://doi.org/10.1097/MPH.0000000000002790

Vancouver

Narvestad-Bøttger H, Winther-Larsen A, Haugbølle Bjerre J, Dziegiel MH, Hansen AT, Hasle H. Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho. Journal of Pediatric Hematology/Oncology. 2024 Jan 1;46(1):E111-E114. https://doi.org/10.1097/MPH.0000000000002790

Author

Narvestad-Bøttger, Helene ; Winther-Larsen, Anne ; Haugbølle Bjerre, Jens ; Dziegiel, Morten Hanefeld ; Hansen, Anne Todsen ; Hasle, Henrik. / Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho. In: Journal of Pediatric Hematology/Oncology. 2024 ; Vol. 46, No. 1. pp. E111-E114.

Bibtex

@article{b31bb4b2b6d2432b96c41546cc5dc381,

title = "Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho",

abstract = "Background: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions. Observations: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×109/L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count. Conclusions: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.",

keywords = "Hb Mizuho, hemoglobinopathy, reticulocytosis, splenectomy",

author = "Helene Narvestad-B{\o}ttger and Anne Winther-Larsen and {Haugb{\o}lle Bjerre}, Jens and Dziegiel, {Morten Hanefeld} and Hansen, {Anne Todsen} and Henrik Hasle",

year = "2024",

month = jan,

day = "1",

doi = "10.1097/MPH.0000000000002790",

language = "English",

volume = "46",

pages = "E111--E114",

journal = "Journal of Pediatric Hematology/Oncology",

issn = "1077-4114",

publisher = "Lippincott Williams & Wilkins",

number = "1",

}

RIS

TY - JOUR

T1 - Extreme Reticulocytosis after Splenectomy in a Patient with Hemoglobin Mizuho

AU - Narvestad-Bøttger, Helene

AU - Winther-Larsen, Anne

AU - Haugbølle Bjerre, Jens

AU - Dziegiel, Morten Hanefeld

AU - Hansen, Anne Todsen

AU - Hasle, Henrik

PY - 2024/1/1

Y1 - 2024/1/1

N2 - Background: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions. Observations: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×109/L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count. Conclusions: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.

AB - Background: Patients with Hb Mizuho may be splenectomized at a young age to decrease their need for blood transfusions. Observations: Transfusion-dependency decreased dramatically in a 4-year-old white boy with Hb Mizuho after splenectomy. Surprisingly, he developed reticulocytosis (>1000×109/L) with a peak reticulocyte percentage of 49%, and erythrocyte abnormalities, including Heinz bodies, Howell-Jolly bodies, and basophilic stippling. Manual reticulocyte counting and flow cytometric measurement with anti-CD71 antibodies supported a truly elevated reticulocyte count. Conclusions: We propose possible explanations for the extreme reticulocytosis that arose postsplenectomy and compare the reticulocyte count in the present case with previously published cases.

KW - Hb Mizuho

KW - hemoglobinopathy

KW - reticulocytosis

KW - splenectomy

UR - http://www.scopus.com/inward/record.url?scp=85181586201&partnerID=8YFLogxK

U2 - 10.1097/MPH.0000000000002790

DO - 10.1097/MPH.0000000000002790

M3 - Journal article

C2 - 38011049

AN - SCOPUS:85181586201

VL - 46

SP - E111-E114

JO - Journal of Pediatric Hematology/Oncology

JF - Journal of Pediatric Hematology/Oncology

SN - 1077-4114

IS - 1

ER -

ID: 398644067

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