Extracellular potassium and blood flow in the post-ischemic rat brain
Research output: Contribution to journal › Journal article › Research › peer-review
The concentration of extracellular potassium, [K+]e, was measured in parietal cortex and basal ganglia of rats during and after ten minutes of complete cerebral ischemia. The post-ischemic normalization of [K+]e was considerably delayed in parietal cortex compared to basal ganglia, but in both regions, [K+]e reached its normal concentration within 4 min of the end of the ischemia. Also, in both regions blood flow was elevated at the time of maximal [K+]e decrease. Our findings suggest that the normalization of [K+]e and cerebrovascular resistance after ischemia are related by positive feed-back, possibly via the stimulation of Na+-K+-ATPase.
Original language | English |
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Journal | Pflügers ARchiv (European Journal of Physiology) |
Volume | 389 |
Issue number | 1 |
Pages (from-to) | 1-7 |
Number of pages | 6 |
ISSN | 1432-2013 |
Publication status | Published - 1980 |
Externally published | Yes |
ID: 14946077