Effekten af statiner på eksacerbationer og dødelighed ved KOL
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Effekten af statiner på eksacerbationer og dødelighed ved KOL. / Damkjær, Mathias; Håkansson, Kjell E J; Ulrik, Charlotte S; Godtfredsen, Nina S.
In: Ugeskrift for Laeger, Vol. 182, No. 23, V10190592, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Effekten af statiner på eksacerbationer og dødelighed ved KOL
AU - Damkjær, Mathias
AU - Håkansson, Kjell E J
AU - Ulrik, Charlotte S
AU - Godtfredsen, Nina S
PY - 2020
Y1 - 2020
N2 - The role of statins on the disease course of COPD is controversial. Observational studies have shown a reduction in mortality and exacerbations, but results of randomised clinical trials (RCTs) of statin treatment and its effect on adverse outcomes are conflicting. Recent meta-analyses suggest the need for further RCTs including COPD patients both with and without concurrent cardiovascular disease (CVD). As there are no known detrimental effects of statins in COPD patients, we conclude in this review, that statins should be prescribed more frequently in these patients due to the common co-morbidity with CVD.
AB - The role of statins on the disease course of COPD is controversial. Observational studies have shown a reduction in mortality and exacerbations, but results of randomised clinical trials (RCTs) of statin treatment and its effect on adverse outcomes are conflicting. Recent meta-analyses suggest the need for further RCTs including COPD patients both with and without concurrent cardiovascular disease (CVD). As there are no known detrimental effects of statins in COPD patients, we conclude in this review, that statins should be prescribed more frequently in these patients due to the common co-morbidity with CVD.
M3 - Tidsskriftartikel
C2 - 32515342
VL - 182
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 23
M1 - V10190592
ER -
ID: 262818243