Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.
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Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain. / Wong, D F; Wagner, H N; Dannals, R F; Links, J M; Frost, J J; Ravert, H T; Wilson, A A; Rosenbaum, A E; Gjedde, A; Douglass, K H.
In: Science, Vol. 226, No. 4681, 1984, p. 1393-6.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain.
AU - Wong, D F
AU - Wagner, H N
AU - Dannals, R F
AU - Links, J M
AU - Frost, J J
AU - Ravert, H T
AU - Wilson, A A
AU - Rosenbaum, A E
AU - Gjedde, A
AU - Douglass, K H
PY - 1984
Y1 - 1984
N2 - D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females.
AB - D2 dopamine and S2 serotonin receptors were imaged and measured in healthy human subjects by positron emission tomography after intravenous injection of 11C-labeled 3-N-methylspiperone. Levels of receptor in the caudate nucleus, putamen, and frontal cerebral cortex declined over the age span studied (19 to 73 years). The decline in D2 receptor in males was different from that in females.
M3 - Journal article
C2 - 6334363
VL - 226
SP - 1393
EP - 1396
JO - Science
JF - Science
SN - 0036-8075
IS - 4681
ER -
ID: 14943673