C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation
Research output: Contribution to journal › Journal article › Research › peer-review
Elevated levels of C reactive protein (CRP) are associated with increased risk of ischaemic vascular disease. We tested whether this is a causal association. CRP > 3 vs < 1 mg/l were associated with an increased risk of ischaemic heart- and cerebrovascular disease of 1.6 and 1.3, respectively. Four CRP polymorphisms were associated with a 64% increase in CRP levels, resulting in a theoretically predicted increased risk of 32% and 25% for ischemic heart- and ischemic cerebrovascular disease, respectively. However, these genotype combinations were not associated with an increased risk of ischaemic vascular disease.
Udgivelsesdato: 2009-May
Udgivelsesdato: 2009-May
Translated title of the contribution | C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication |
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Original language | Danish |
Journal | Ugeskrift for læger |
Volume | 171 |
Issue number | 21 |
Pages (from-to) | 1751-5 |
Number of pages | 5 |
ISSN | 0041-5782 |
Publication status | Published - 2009 |
Bibliographical note
Keywords: Atherosclerosis; Biological Markers; C-Reactive Protein; Cerebrovascular Disorders; Cohort Studies; Genetic Predisposition to Disease; Genotype; Humans; Myocardial Ischemia; Polymorphism, Genetic; Risk Factors
ID: 20321552