Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa
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Despite their well-established functional roles, histone modifications have received less attention than DNA methylation in the cancer field. In order to evaluate their importance in colorectal cancer (CRC), we generated the first genome-wide histone modification profiles in paired normal colon mucosa and tumor samples.
Original language | English |
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Article number | 450 |
Journal | B M C Cancer |
Volume | 11 |
Number of pages | 13 |
ISSN | 1471-2407 |
DOIs | |
Publication status | Published - 2011 |
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