Body composition growth patterns in early infancy: A latent class trajectory analysis of the Ethiopian iABC Birth Cohort
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Body composition growth patterns in early infancy : A latent class trajectory analysis of the Ethiopian iABC Birth Cohort. / Andersen, Gregers Stig; Wibæk Christensen, Rasmus; Kaestel, Pernille; Girma, Tsinuel; Admassu, Bitiya; Abera, Mubarek; Vistisen, Dorte; Jørgensen, Marit Eika; Michaelsen, Kim F.; Friis, Henrik; Wells, Jonathan C K.
In: Obesity, Vol. 26, No. 7, 2018, p. 1225-1233.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Body composition growth patterns in early infancy
T2 - A latent class trajectory analysis of the Ethiopian iABC Birth Cohort
AU - Andersen, Gregers Stig
AU - Wibæk Christensen, Rasmus
AU - Kaestel, Pernille
AU - Girma, Tsinuel
AU - Admassu, Bitiya
AU - Abera, Mubarek
AU - Vistisen, Dorte
AU - Jørgensen, Marit Eika
AU - Michaelsen, Kim F.
AU - Friis, Henrik
AU - Wells, Jonathan C K
N1 - CURIS 2018 NEXS 182
PY - 2018
Y1 - 2018
N2 - Objective: The objective of this study was to identify subgroups with distinct fat and fat-free growth patterns in the first 6 months of life and describe predictors of these different patterns.Methods: A total of 510 apparently healthy Ethiopian infants were followed from birth to 6 months of age. Each infant had at least three and up to six repeated measurements of fat and fat-free mass using air-displacement plethysmography. Latent class trajectory analyses were used to categorize infants in groups with distinct body composition patterns.Results: Four distinct fat mass and two fat-free mass growth patterns were identified. Of the infants measured, 5% presented a delayed fat growth pattern and 3% presented a catch-up fat growth pattern involving low birth weight but a significant fat growth velocity from 2.5 to 6 months. A large class had a high fat level at birth and an accelerated fat growth pattern in early infancy. Fat-free growth was represented by two distinct classes with less variability. Catch-up growth was primarily seen in fat mass.Conclusions: We identified distinct patterns of delayed, catch-up, and accelerated fat growth in early infancy. This variability is not detected in regular anthropometric assessment and could be a mechanism linking early growth with later obesity and cardiometabolic risk.
AB - Objective: The objective of this study was to identify subgroups with distinct fat and fat-free growth patterns in the first 6 months of life and describe predictors of these different patterns.Methods: A total of 510 apparently healthy Ethiopian infants were followed from birth to 6 months of age. Each infant had at least three and up to six repeated measurements of fat and fat-free mass using air-displacement plethysmography. Latent class trajectory analyses were used to categorize infants in groups with distinct body composition patterns.Results: Four distinct fat mass and two fat-free mass growth patterns were identified. Of the infants measured, 5% presented a delayed fat growth pattern and 3% presented a catch-up fat growth pattern involving low birth weight but a significant fat growth velocity from 2.5 to 6 months. A large class had a high fat level at birth and an accelerated fat growth pattern in early infancy. Fat-free growth was represented by two distinct classes with less variability. Catch-up growth was primarily seen in fat mass.Conclusions: We identified distinct patterns of delayed, catch-up, and accelerated fat growth in early infancy. This variability is not detected in regular anthropometric assessment and could be a mechanism linking early growth with later obesity and cardiometabolic risk.
U2 - 10.1002/oby.22197
DO - 10.1002/oby.22197
M3 - Journal article
C2 - 29845756
VL - 26
SP - 1225
EP - 1233
JO - Obesity
JF - Obesity
SN - 1930-7381
IS - 7
ER -
ID: 197432671