Analogues of [3H] chloramphenicol for photoaffinity labeling
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Analogues of [3H] chloramphenicol for photoaffinity labeling. / Hansen, J B; Nielsen, Peter E.; Leick, V; Buchardt, O.
In: Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, Vol. 360, No. 6, 06.1979, p. 721-4.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Analogues of [3H] chloramphenicol for photoaffinity labeling
AU - Hansen, J B
AU - Nielsen, Peter E.
AU - Leick, V
AU - Buchardt, O
PY - 1979/6
Y1 - 1979/6
N2 - The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.
AB - The synthesis of [3H]chloramphenicol and its erythro-diastereoisomer with specific activities of 1.25 Ci/mmol, and the further transformation of the [3H]chloramphenicol to a series of azido and diazo-substituted derivatives are described. The antibiotic activity of the compounds was considered insufficient for their use as photoaffinity labels.
KW - Affinity Labels
KW - Chemical Phenomena
KW - Chemistry
KW - Chloramphenicol/analogs & derivatives
KW - Escherichia coli/drug effects
KW - Isotope Labeling/methods
KW - Ribosomes/drug effects
KW - Tritium
U2 - 10.1515/bchm2.1979.360.1.721
DO - 10.1515/bchm2.1979.360.1.721
M3 - Journal article
C2 - 381142
VL - 360
SP - 721
EP - 724
JO - Biological Chemistry
JF - Biological Chemistry
SN - 1431-6730
IS - 6
ER -
ID: 203631991