Alfa-1-antitrypsinmangel
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Alfa-1-antitrypsinmangel. / de Vos, Jesper Dichmann; Hillberg, Ole; Perch, Michael; Jensen, Jens-Ulrik; Wilcke, Jon Torgny; Løkke, Anders.
In: Ugeskrift for Laeger, Vol. 183, No. 30, V02210150, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Alfa-1-antitrypsinmangel
AU - de Vos, Jesper Dichmann
AU - Hillberg, Ole
AU - Perch, Michael
AU - Jensen, Jens-Ulrik
AU - Wilcke, Jon Torgny
AU - Løkke, Anders
PY - 2021
Y1 - 2021
N2 - The subject of this review is alpha-1-antitrypsin deficiency (A1AD), which is a rare hereditary disease with great impact in adults, especially smokers, quality of life and longevity. Early diagnosis is crucial for treatment outcome. The primary care physician should refer patients younger than 50-years-old with COPD or emphysema, familiar accumulation of A1AD or liver cirrhosis of unknown cause. Most important treatment is smoking cessation, pulmonary rehabilitation and inhaled medication according to current guidelines. Substitution treatment with alpha-1-antitrypsin is now an option after its approval by the Danish medical council in January 2020.
AB - The subject of this review is alpha-1-antitrypsin deficiency (A1AD), which is a rare hereditary disease with great impact in adults, especially smokers, quality of life and longevity. Early diagnosis is crucial for treatment outcome. The primary care physician should refer patients younger than 50-years-old with COPD or emphysema, familiar accumulation of A1AD or liver cirrhosis of unknown cause. Most important treatment is smoking cessation, pulmonary rehabilitation and inhaled medication according to current guidelines. Substitution treatment with alpha-1-antitrypsin is now an option after its approval by the Danish medical council in January 2020.
KW - Adult
KW - Humans
KW - Liver Cirrhosis
KW - Middle Aged
KW - Pulmonary Emphysema/etiology
KW - Quality of Life
KW - Smoking Cessation
KW - alpha 1-Antitrypsin Deficiency/complications
M3 - Tidsskriftartikel
C2 - 34356027
VL - 183
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 30
M1 - V02210150
ER -
ID: 288056330